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Mapping of several bone diseases onto levels of vitamin D (calcidiol) in the blood [6] Normal bone vs. osteoporosis. Vitamin D deficiency is typically diagnosed by measuring the concentration of the 25-hydroxyvitamin D in the blood, which is the most accurate measure of stores of vitamin D in the body.
The structural difference between vitamin D 2 and vitamin D 3 lies in the side chain: vitamin D 2 has a double bond between carbons 22 and 23, and a methyl group on carbon 24. Vitamin D analogues have also been synthesized.
Vitamin D (the inactive version) is mainly from two forms: vitamin D 3 and vitamin D 2. Vitamin D 3, or cholecalciferol, is formed in the skin after exposure to sunlight or ultra violet radiation or from D 3 supplements or fortified food sources. Vitamin D 2, or ergocalciferol, is obtained from D 2 supplements or fortified food sources. [3]
The U.S. Preventive Services Task Force say vitamin D supplements do not reduce the risk of falls or bone fractures in healthy older adults. The draft recommendation notes vitamin D can be helpful ...
Vitamin D supplements, with or without calcium, are important for overall health. However, vitamin D supplements have no effect on preventing falls or fractures in older adults, according to the U ...
Effects of low dose vs. high dose vitamin D In this double-blind, randomized controlled trial (RCT), researchers examined 221 adults ages 65 years or older who had BMIs over 25 and were considered ...
Vitamin D compounds, specifically cholecalciferol (D3) and ergocalciferol (D2), are used in rodenticides due to their ability to induce hypercalcemia, a condition characterized by elevated calcium levels in the blood. This overdose leads to organ failure and is pharmacologically similar to vitamin D's toxic effects in humans.
Signs of vitamin D deficiency include fatigue, depression, and bone weakness. Dr. Tolliver says the best way to know if you’re deficient is through a blood test at your doctor’s office.
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