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  2. Threshold dose - Wikipedia

    en.wikipedia.org/wiki/Threshold_dose

    Threshold dose is the minimum dose of drug that triggers minimal detectable biological effect in an animal. [1] At extremely low doses, biological responses are absent for some of the drugs. The increase in dose above threshold dose induces an increase in the percentage of biological responses. [ 2 ]

  3. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    Some patients request to be switched to a different narcotic due to stigma associated with a particular drug (e.g. a patient refusing methadone due to its association with opioid addiction treatment). [4] Equianalgesic charts are also used when calculating an equivalent dosage of the same drug, but with a different route of administration.

  4. Polysulfated glycosaminoglycan - Wikipedia

    en.wikipedia.org/wiki/Polysulfated_glycosaminoglycan

    Side effects from intra-articular administration can include joint pain, swelling, lameness, and, rarely, infection of the joint. Intramuscular injection can cause dose-dependent inflammation and bleeding, since PSGAG is an analogue of the anticoagulant heparin. [4] In dogs, this may manifest as bleeding from the nose or as bloody stools. [7]

  5. Pain management in children - Wikipedia

    en.wikipedia.org/wiki/Pain_management_in_children

    Used as treatment for pain and as an anti-inflammatory. Can be administered as oral tablet or liquid. It is recommended to use the lowest dose and shortest duration possible to control pain. NSAIDs are not approved for infants under 3 months old. General adverse effects for NSAIDs: Renal impairment; Hepatic impairment

  6. Clark's rule - Wikipedia

    en.wikipedia.org/wiki/Clark's_rule

    Clark's rule is a medical term referring to a mathematical formula used to calculate the proper dosage of medicine for children aged 2–17 based on the weight of the patient and the appropriate adult dose. [1] The formula was named after Cecil Belfield Clarke (1894–1970), a Barbadian physician who practiced throughout the UK, the West Indies ...

  7. Anti-inflammatory - Wikipedia

    en.wikipedia.org/wiki/Anti-inflammatory

    Anti-inflammatory or antiphlogistic is the property of a substance or treatment that reduces inflammation or swelling. Anti-inflammatory drugs , also called anti-inflammatories , make up about half of analgesics .

  8. Juvenile idiopathic arthritis - Wikipedia

    en.wikipedia.org/wiki/Juvenile_idiopathic_arthritis

    Juvenile, in this context, refers to disease onset before 16 years of age, while idiopathic refers to a condition with no defined cause, and arthritis is inflammation within the joint. [4] JIA is an autoimmune, noninfective, inflammatory joint disease, the cause of which remains poorly understood. It is characterised by chronic joint inflammation.

  9. Dog health - Wikipedia

    en.wikipedia.org/wiki/Dog_health

    The lethal dose for 50% of dogs is 100 – 200 mg per kilogram (kg) of body weight, yet some dogs will exhibit signs of toxicosis after ingesting as little as 20 mg per kg. [38] In case of accidental intake of chocolate, especially involving a smaller dog, contact a veterinarian or animal poison control immediately; it is commonly recommended ...

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