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Results released in February 2009 from a clinical trial of PRO 2000 (Indevus Pharmaceuticals), a vaginal-microbicide gel (0.5%), sparked hope that it might provide modest protection against HIV. [22] The results of a larger trial released in December 2009 showed that PRO 2000 was safe as administered, but was ineffective in reducing the risk of ...
The ideal vaginal microbicide would have the following characteristics: provide protection against infection not require application at the time of intercourse not harm the natural tissue [3] As of 2009, not harming natural tissue was the most troublesome aspect of development.
NES/T (Nesterone/Testosterone gel) is a transdermal gel that users apply to the upper arms and shoulders once daily. [ 77 ] [ 78 ] Developed as a collaboration between the NICHD and Population Council , NES/T is in a phase II clinical trial, [ 79 ] where it is being evaluated for safety and efficacy, with healthy couples relying on it as their ...
The trial involved 222 men, ages 18 to 50, who applied 5 milliliters of the gel (about a teaspoon) to each of their shoulder blades once per day. The second part of the two-part trial is still ...
Pre-filled syringes of vaginal tightening gel. Over 2,500 syringes filled with dangerous “vaginal tightening gel,” coming from Hong Kong, were seized at the Minneapolis-St. Paul Airport.
[15] [16] [17] The compound was being used as a vaginal antiseptic by the late 1800s. [18] Clinical studies of boric acid for treatment of vaginal infections began being published in the late 1900s and early 2000s. [5] Despite not being a pharmaceutical drug, boric acid is widely used by women in the management of vaginal infections.
Nonoxynol-9 is a common ingredient of most vaginal and anal lubricants due to its spermicidal properties. A 2004 study found that over a six-month period, the typical-use failure rates for five nonoxynol-9 vaginal contraceptives (film, suppository, and gels at three different concentrations) ranged from 10% to 20%.
Povidone-iodine (PVP-I), also known as iodopovidone, is an antiseptic used for skin disinfection before and after surgery. [1] [2] It may be used both to disinfect the hands of healthcare providers and the skin of the person they are caring for. [2]
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