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Premature adrenarche is the most common cause of the early appearance of pubic hair ("premature pubarche") in childhood. In a large proportion of children it seems to be a variation of normal development requiring no treatment. However, there are three clinical issues related to premature adrenarche.
CDGP is a conditions characterized by an extreme variation from the normal timing of puberty. Both gonadarche and adrenarche are delayed in this case, resulting in some children developing later than others. There is a delay in the development of the reproductive organs and adrenal glands seen in children with CDGP.
However, premature pubarche may also arise independently of adrenarche. Premature pubarche is a subset of precocious puberty which divide into 1) true precocious puberty that includes complete and central precocious puberty and 2) incomplete puberty which has 3 subsets: premature thelacrche, premature pubarche and isolated menarche. [13]
Congenital adrenal hyperplasia due to 3β-hydroxysteroid dehydrogenase deficiency is an uncommon form of congenital adrenal hyperplasia (CAH) resulting from a mutation in the gene for one of the key enzymes in cortisol synthesis by the adrenal gland, 3β-hydroxysteroid dehydrogenase (3β-HSD) type II ().
The term is used with several slightly different meanings that are usually apparent from the context. In its broadest sense, and often simplified as early puberty , "precocious puberty" sometimes refers to any physical sex hormone effect, due to any cause, occurring earlier than the usual age, especially when it is being considered as a medical ...
D.C. firefighters said a vehicle plunged into the Potomac River after being involved in a crash the Arlington Memorial Bridge. Police are investigating whether wintry weather played a role in the ...
The latter has the same biological activity as testosterone [6] and, therefore, these are also very important in healthy individuals and patients with diseases like, congenital adrenal hyperplasia, polycystic ovarian syndrome, or premature adrenarche. [6] Determined by consideration of all biological assay methods (c. 1970): [7]
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