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After the publication of the NIH-run antidepressant clinical trial, clinics began opening in which the intravenous ketamine is given for depression. [5] [6] This practice is an off label use of IV ketamine in the United States, though the intranasal version of esketamine has been approved by the FDA for treatment of depression [5] [7] In 2015 there were about 60 such clinics in the US; the ...
A slightly different version of ketamine, called esketamine or Spravato, was approved by the FDA in 2019 for treatment-resistant depression. Esketamine is given as a nasal spray and must be ...
The only form of ketamine that is FDA-approved for treatment-resistant depression is Spravato, which includes one molecule of ketamine and only comes in the form of a nasal spray.
Over the last few years, growing research has found that the drug also works for treatment-resistant depression in some people, which led the FDA to approve a version called esketamine, or ...
Ketamine is a dissociative anesthetic used medically for induction and maintenance of anesthesia. It is also used as a treatment for depression and in pain management. [19] Ketamine is an NMDA receptor antagonist which accounts for most of its psychoactive effects. [20]
The Oxford Health NHS Foundation Trust website says ketamine is a licensed anaesthetic drug that can also be used as an “off-label” treatment for depression, because it has not been licensed ...
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