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  2. RNA silencing - Wikipedia

    en.wikipedia.org/wiki/RNA_silencing

    RNA silencing describes several mechanistically related pathways which are involved in controlling and regulating gene expression. [5] [6] [7] RNA silencing pathways are associated with the regulatory activity of small non-coding RNAs (approximately 20–30 nucleotides in length) that function as factors involved in inactivating homologous sequences, promoting endonuclease activity ...

  3. RNA-induced silencing complex - Wikipedia

    en.wikipedia.org/wiki/RNA-induced_silencing_complex

    The RNA-induced silencing complex, or RISC, is a multiprotein complex, specifically a ribonucleoprotein, which functions in gene silencing via a variety of pathways at the transcriptional and translational levels. [1]

  4. RNA interference - Wikipedia

    en.wikipedia.org/wiki/RNA_interference

    RNA interference (RNAi) is a biological process in which RNA molecules are involved in sequence-specific suppression of gene expression by double-stranded RNA, through translational or transcriptional repression. Historically, RNAi was known by other names, including co-suppression, post-transcriptional gene silencing (PTGS), and quelling. The ...

  5. RNA-induced transcriptional silencing - Wikipedia

    en.wikipedia.org/wiki/RNA-induced...

    RNA-induced transcriptional silencing (RITS) is a form of RNA interference by which short RNA molecules – such as small interfering RNA (siRNA) – trigger the downregulation of transcription of a particular gene or genomic region.

  6. Small interfering RNA - Wikipedia

    en.wikipedia.org/wiki/Small_interfering_RNA

    Mediating RNA interference in cultured mammalian cells. Small interfering RNA (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of double-stranded non-coding RNA molecules, typically 20–24 base pairs in length, similar to microRNA (miRNA), and operating within the RNA interference (RNAi) pathway.

  7. RNA - Wikipedia

    en.wikipedia.org/wiki/RNA

    RNA and deoxyribonucleic ... were shown by Jeannie T. Lee and others to be the silencing of blocks of chromatin via recruitment of ... Wikipedia® is a registered ...

  8. microRNA - Wikipedia

    en.wikipedia.org/wiki/MicroRNA

    The actual work of RNA silencing is performed by RISC in which the main catalytic subunit is one of the Argonaute proteins (AGO), and miRNA serves as a template for recognizing specific mRNA sequences. The function of miRNAs appears to be in gene regulation. For that purpose, a miRNA is complementary to a part of one or more messenger RNAs (mRNAs).

  9. RNA silencing suppressor p19 - Wikipedia

    en.wikipedia.org/wiki/RNA_silencing_suppressor_p19

    RNA silencing suppressor p19 (also known as Tombusvirus P19 core protein and 19 kDa symptom severity modulator) is a protein expressed from the ORF4 gene in the genome of tombusviruses. These viruses are positive-sense single-stranded RNA viruses that infect plant cells, in which RNA silencing forms a