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Lorcaserin, marketed under the brand name Belviq, [4] [5] was a weight-loss drug developed by Arena Pharmaceuticals.It reduces appetite by activating serotonin receptor the 5-HT 2C receptor in the hypothalamus, a region of the brain which is known to control appetite. [6]
The Food and Drug Administration approved the weight-loss therapy Belviq from Arena Pharmaceuticals in June 2012. It took nearly one year for the company to gain marketing approval, but Belviq's ...
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GLP-1 medications are breakthroughs for weight loss, diabetes, and more. Pharma companies are clamoring to produce pills or longer-lasting drugs with faster effects. Novo Nordisk, Eli Lilly ...
Weight loss drugs have been developed since the early twentieth century, and many have been banned or withdrawn from the market due to adverse effects, including deaths; other drugs proved ineffective. Although many earlier drugs were stimulants such as amphetamines, in the early 2020s, GLP-1 receptor agonists became popular for weight loss.
The development of 5-HT 2C receptor knockout mice in the mid-1990s was a hallmark achievement in the identification and development of serotonergic drugs for weight loss. These knockout mice were hyperphagic , which led to obesity, partial Leptin resistance, increased adipose deposition, insulin resistance, and impaired glucose tolerance.
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3579 S High St, Columbus, OH · Directions · (614) 409-0683- 1540 Olentangy River Rd, Columbus, OH · Directions · (614) 299-2253