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  2. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Rivaroxaban (Xarelto) was the first approved FXa inhibitor to become commercially available in Europe and Canada in 2008. [1] The second one was apixaban (Eliquis), approved in Europe in 2011 [2] and in the United States in 2012. [3] The third one edoxaban (Lixiana, Savaysa) was approved in Japan in 2011 and in Europe and the US in 2015. [4]

  3. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Side effects may include bleeding, most commonly from the nose, gastrointestinal tract (GI) or genitourinary system. [2] Compared to the risk of bleeding with warfarin use, direct factor Xa inhibitors have a higher risk of GI bleeding, but lower risk of bleeding in the brain. [2]

  4. Rivaroxaban - Wikipedia

    en.wikipedia.org/wiki/Rivaroxaban

    Rivaroxaban, sold under the brand name Xarelto among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots. [8] Specifically it is used to treat deep vein thrombosis and pulmonary emboli and prevent blood clots in atrial fibrillation and following hip or knee surgery. [ 8 ]

  5. Factbox-Top Medicare drugs headed for price cuts - AOL

    www.aol.com/news/factbox-top-medicare-drugs...

    Eliquis rival Xarelto from Johnson & Johnson cost Medicare more than $6 billion between June 2022 and May 2023. The bloodthinner, which was used to treat 1.3 million enrollees, can lower the risk ...

  6. J&J, Bristol Myers lose challenges to US drug price ...

    www.aol.com/news/j-j-bristol-myers-lose...

    Eliquis brought Bristol Myers about $8.52 billion in U.S. sales last year, while J&J recorded $2.36 billion in Xarelto sales. Eliquis is shared with Pfizer and Xarelto with Bayer, which were not ...

  7. Why Wall Street is unfazed by Medicare drug pricing threat - AOL

    www.aol.com/finance/why-wall-street-unfazed...

    Eliquis brought in $3.4 billion for the company in the second quarter, an increase of 7% year over year. It contributed $12.2 billion , or almost a quarter, of BMS's $45 billion in revenues in 2023.

  8. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    Apixaban, sold under the brand name Eliquis, is an anticoagulant medication used to treat and prevent blood clots and to prevent stroke in people with nonvalvular atrial fibrillation through directly inhibiting factor Xa.

  9. Biden administration says Medicare negotiated price discounts ...

    www.aol.com/biden-administration-says-medicare...

    Older Americans on Medicare who take 10 widely prescribed drugs such as Xarelto or Eliquis will get a break on the medications' list prices beginning in 2026. ... Eliquis, a blood thinner from ...

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