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HBsAg (also known as the Australia antigen) is the surface antigen of the hepatitis B virus (HBV). Its presence in blood indicates existing hepatitis B infection. Structure and function
If the host is able to clear the infection, eventually the HBsAg will become undetectable and will be followed by IgG antibodies to the hepatitis B surface antigen and core antigen (anti-HBs and anti HBc IgG). [39] The time between the removal of the HBsAg and the appearance of anti-HBs is called the window period. A person negative for HBsAg ...
The presence of surface antibody (anti-HBs) indicates an individual with immunity to hepatitis B, whether due to previously resolved infection or due to hepatitis B vaccination. [65] For example, an individual who has never had any exposure to HBV, either by vaccine or by infection, would test negative for the entire serology panel.
This news follows the company’s recent announcement of new data from its Phase 2 study of BJT-778, a best-in class investigational, fully human, high-affinity monoclonal antibody (mAb) that targets hepatitis B virus surface antigen (anti-HBsAg), as a potential monotherapy for adults with chronic hepatitis D (CHD). Bluejay is advancing BJT-778 ...
An antibody level between 10 and 100 ... The recombinant vaccine is based on Hepatitis B surface antigen gene inserted into yeast (Saccharomyces cerevisiae) ...
HBsAg (hepatitis B surface antigen) was the first hepatitis B virus protein to be discovered. [15] It consists of small (S), medium (M) and large (L) protein. [16] HBcAg (hepatitis B core antigen) is the main structural protein of HBV icosahedral nucleocapsid and it has function in replication of the virus. [17]
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