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2. Iron overload - Wikipedia

   en.wikipedia.org/wiki/Iron_overload

   Iron overload (also known as haemochromatosis or hemochromatosis) is the abnormal and increased accumulation of total iron in the body, leading to organ damage. [1] The primary mechanism of organ damage is oxidative stress, as elevated intracellular iron levels increase free radical formation via the Fenton reaction.

3. Serum iron - Wikipedia

   en.wikipedia.org/wiki/Serum_iron

   Serum iron is a medical laboratory test that measures the amount of circulating iron that is bound to transferrin and freely circulate in the blood. Clinicians order this laboratory test when they are concerned about iron deficiency, which can cause anemia and other problems. 65% of the iron in the body is bound up in hemoglobin molecules in red blood cells.

4. Transferrin saturation - Wikipedia

   en.wikipedia.org/wiki/Transferrin_saturation

   For instance, a value of 15% means that 15% of iron-binding sites of transferrin are being occupied by iron. The three results are usually reported together. A low transferrin saturation is a common indicator of iron deficiency anemia whereas a high transferrin saturation may indicate iron overload or hemochromatosis.

5. Iron deficiency in adults may be more common than thought ...

   www.aol.com/news/iron-deficiency-adults-may-more...

   An analysis of data from more than 8,000 adults in the U.S. revealed that 14% had low iron blood levels, a condition known as absolute iron deficiency, while 15% had the right iron levels but ...

6. Hemosiderosis - Wikipedia

   en.wikipedia.org/wiki/Hemosiderosis

   The aims of iron chelation therapy include (a) prevention therapy in order to minimize the risk of onset of iron-mediated complications, (b) rescue therapy for the removal of storage iron and (c) emergency therapy if heart failure develops or if there is a downward trend of left ventricular (LV) function that requires hospitalisation using ...

7. Antioxidant-rich diet may reduce risk of iron buildup ... - AOL

   www.aol.com/antioxidant-rich-diet-may-reduce...

   The body mainly uses iron to create a protein found in red blood cells called hemoglobin, which is tasked with carrying oxygen from the lungs to other areas of the body. Additionally, iron helps ...

8. Human iron metabolism - Wikipedia

   en.wikipedia.org/wiki/Human_iron_metabolism

   Human iron metabolism is the set of chemical reactions that maintain human homeostasis of iron at the systemic and cellular level. Iron is both necessary to the body and potentially toxic. Controlling iron levels in the body is a critically important part of many aspects of human health and disease.

9. Hereditary haemochromatosis - Wikipedia

   en.wikipedia.org/wiki/Hereditary_haemochromatosis

   Normally, HFE facilitates the binding of transferrin, which is iron's carrier protein in the blood. Transferrin levels are typically elevated at times of iron depletion (low ferritin stimulates the release of transferrin from the liver). When transferrin is high, HFE works to increase the intestinal release of iron into the blood.