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Testosterone is the primary male sex hormone and androgen in males. [3] In humans, testosterone plays a key role in the development of male reproductive tissues such as testicles and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of body hair.
The main male sex organs are the penis and the scrotum, which contains the testicles that produce semen and sperm, which, as part of sexual intercourse, fertilize an ovum in the female's body; the fertilized ovum develops into a fetus, which is later born as an infant. The corresponding system in females is the female reproductive system.
5-DHT or DHT is a male reproductive hormone that targets the prostate gland, bulbourethral gland, seminal vesicles, penis and scrotum and promotes growth/mitosis/cell maturation and differentiation. Testosterone is converted to 5-DHT by 5alpha-reductase, usually with in the target tissues of 5-DHT because of the need for high concentrations of ...
This action of androgens is supported by a hormone from Sertoli cells, Müllerian inhibitory hormone (MIH), which prevents the embryonic Müllerian ducts from developing into fallopian tubes and other female reproductive tract tissues in male embryos. MIH and androgens cooperate to allow for movement of testes into the scrotum.
Endocrine hormones are a well-known and critical controlling factor in the normal differentiation of the reproductive system. [8] The Wolffian duct forms the epididymis, vas deferens, ejaculatory duct, and seminal vesicle in the male reproductive system, but essentially disappears in the female reproductive system. [9]
The reproductive system of an organism, also known as the genital system, is the biological system made up of all the anatomical organs involved in sexual reproduction. Many non-living substances such as fluids, hormones , and pheromones are also important accessories to the reproductive system. [ 1 ]
The metabolic clearance rate of a steroid is defined as the volume of blood that has been completely cleared of the hormone per unit time. The production rate of a steroid hormone refers to entry into the blood of the compound from all possible sources, including secretion from glands and conversion of prohormones into the steroid of interest ...
Testosterone serves as one of the major sexual reproductive hormones in the male reproductive system However, the enzyme aromatase is present in testes and capable of synthesizing estrogens from androgens. [2] Estrogens are present in high concentrations in luminal fluids of the male reproductive tract. [5]