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Pien Tze Huang (片仔癀; Piànzǎihuáng) is a traditional Chinese herbal formula first documented during the Ming Dynasty and historically used to combat inflammation. In recent years it has been tested on animals for its benefits against various diseases such as multiple sclerosis, cerebral ischemia, carbon-induced liver damage, and cancer.
A single slice (68 g) of beef liver exceeds the tolerable upper intake level of vitamin A (6410 μg preformed vs. UL for preformed = 3000 μg). [4] 100 g cod liver contains 5 mg of vitamin A and 100 μg of vitamin D. [5] Liver contains large amounts of vitamin B 12, and this was one of the factors that led to the discovery of the vitamin. [6]
Liver regeneration is the process by which the liver is able to replace damaged or lost liver tissue. The liver is the only visceral organ with the capacity to regenerate. [ 1 ] [ 2 ] The liver can regenerate after partial hepatectomy or injury due to hepatotoxic agents such as certain medications, toxins, or chemicals. [ 3 ]
In chronic liver diseases such as cirrhosis, bile acids may deposit in the skin, causing pruritus (itching). Hence, bile acid sequestrants may be used for the prevention of pruritus in patients with chronic liver disease. [10] Bile acid sequestrants may also be used to treat hyperthyroidism as an adjunct therapy.
Ursodeoxycholic acid (UDCA), also known as ursodiol, is a secondary bile acid, produced in humans and most other species from metabolism by intestinal bacteria.It is synthesized in the liver in some species, and was first identified in bile of bears of genus Ursus, from which its name derived. [8]
The senator Robert Byrd, after winning re-election in 2000, is quoted as saying, "West Virginia has always had four friends, God Almighty, Sears Roebuck, Carter's Liver Pills and Robert C. Byrd." [6] A Carter's Little Liver Pills ad was featured in Joe Dante's 1968 collage parody film The Movie Orgy. [7]
Enterohepatic circulation of drugs. Enterohepatic circulation is the circulation of biliary acids, bilirubin, drugs or other substances from the liver to the bile, followed by entry into the small intestine, absorption by the enterocyte and transport back to the liver.
It is a tri-hydroxy-bile acid with 3 hydroxyl groups (3α, 7α and 12α). In its synthesis in the liver, 12α hydroxylation is performed by the additional action of CYP8B1. As this had already been described, the discovery of chenodeoxycholic acid (with 2 hydroxyl groups) made this new bile acid a "deoxycholic acid" in that it had one fewer ...