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A seizure is a paroxysmal episode of symptoms or altered behavior arising from abnormal excessive or synchronous brain neuronal activity. [5] A focal onset seizure arises from a biological neural network within one cerebral hemisphere, while a generalized onset seizure arises from within the cerebral hemispheres rapidly involving both hemispheres.
Over time, the motor seizures become more severe, ultimately culminating in the development of spontaneous seizures (see Pinel's stages below). [6] Though developed in the rat electrical kindling model, the Racine scale has been adapted for other seizure models (e.g. chemical status epilepticus) as well as other species.
A seizure is a sudden change in behavior, movement or consciousness due to abnormal electrical activity in the brain. [3] [6] Seizures can look different in different people.. It can be uncontrolled shaking of the whole body (tonic-clonic seizures) or a person spacing out for a few seconds (absence seizure
Epilepsy can often be confirmed with an EEG, but a normal reading does not rule out the condition. [4] Epilepsy that occurs as a result of other issues may be preventable. [1] Seizures are controllable with medication in about 69% of cases; [7] inexpensive anti-seizure medications are often available. [1]
Breakthrough seizures are more likely with a number of triggers. [54]: 57 Often when a breakthrough seizure occurs in a person whose seizures have always been well controlled, there is a new underlying cause to the seizure. [55] Breakthrough seizures vary. Studies have shown the rates of breakthrough seizures ranging from 11 to 37%. [56]
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Status epilepticus (SE), or status seizure, is a medical condition with abnormally prolonged seizures. It can have long-term consequences, [ 3 ] manifesting as a single seizure lasting more than a defined time (time point 1), or 2 or more seizures over the same period without the person returning to normal between them.
The term seizure threshold is used to describe the balance between excitatory (glutaminergic) and inhibitory (GABA-ergic) forces in the brain which affect how susceptible a person is to seizures. Those diagnosed with epilepsy or certain other neurological conditions are more vulnerable to seizures if the threshold is reduced, and should be ...
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