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Phosgene is used to produce chloroformates such as benzyl chloroformate: R−OH + COCl 2 → R−O−C(=O)−Cl + HCl. In these syntheses, phosgene is used in excess to prevent formation of the corresponding carbonate ester. With amino acids, phosgene (or its trimer) reacts to give amino acid N-carboxyanhydrides. More generally, phosgene acts ...
Phosgene oxime, or CX, is an organic compound with the formula Cl 2 C=N−O H. It is a potent chemical weapon, specifically a nettle agent. The compound itself is a colorless solid, but impure samples are often yellowish liquids. It has a strong, disagreeable and irritating odor. It is used as a reagent in organic chemistry. [2]
A chemical weapon agent (CWA), or chemical warfare agent, is a chemical substance whose toxic properties are meant to kill, injure or incapacitate human beings.About 70 different chemicals have been used or stockpiled as chemical weapon agents during the 20th century, although the Organisation for the Prohibition of Chemical Weapons (OPCW) has an online database listing 35,942 chemicals which ...
Nerve agents, sometimes also called nerve gases, are a class of organic chemicals that disrupt the mechanisms by which nerves transfer messages to organs. The disruption is caused by the blocking of acetylcholinesterase (AChE), an enzyme that catalyzes the breakdown of acetylcholine, a neurotransmitter.
In the treatment of nerve agent poisoning, atropine is most often administered along with a Hagedorn oxime such as pralidoxime, obidoxime, TMB-4, or HI-6, which reactivates acetylcholinesterase which has been inactivated by phosphorylation by an organophosphorus nerve agent and relieves the respiratory muscle paralysis caused by some nerve agents.
A chemical weapon (CW) is a specialized munition that uses chemicals formulated to inflict death or harm on humans. According to the Organisation for the Prohibition of Chemical Weapons (OPCW), this can be any chemical compound intended as a weapon "or its precursor that can cause death, injury, temporary incapacitation or sensory irritation through its chemical action.
In the United States military, the Mark I NAAK, or MARK I Kit, ("Nerve Agent Antidote Kit") is a dual-chamber autoinjector: Two anti-nerve agent drugs—atropine sulfate and pralidoxime chloride—each in injectable form, constitute the kit. The kits are only effective against the nerve agents tabun (GA), sarin (GB), soman (GD) and VX.
Green Cross (Grünkreuz) is a World War I chemical warfare pulmonary agent consisting of chloropicrin (PS, Aquinite, Klop), phosgene (CG, Collongite) and/or trichloromethyl chloroformate (Surpalite, Perstoff). Green Cross is also a generic World War I German marking for artillery shells with pulmonary agents (chemical payload affecting the ...