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Constitutional Symptoms. Unexplained pain: Pain that persists, has no clear cause, and does not respond to treatment may be a warning sign of many types of cancers. Unexplained night sweats or fever: These may be signs of an immune system cancer. Fever in children rarely points to malignancy, but may merit evaluation.
Chronic progressive external ophthalmoplegia ( CPEO) is a type of eye disorder characterized by slowly progressive inability to move the eyes and eyebrows. [ 1] It is often the only feature of mitochondrial disease, in which case the term CPEO may be given as the diagnosis. In other people suffering from mitochondrial disease, CPEO occurs as ...
Frequency. ~2% (children) [ 3] Strabismus is a vision disorder in which the eyes do not properly align with each other when looking at an object. [ 2] The eye that is pointed at an object can alternate. [ 3] The condition may be present occasionally or constantly. [ 3] If present during a large part of childhood, it may result in amblyopia, or ...
Specialty. Ophthalmology. Exotropia is a form of strabismus where the eyes are deviated outward. It is the opposite of esotropia and usually involves more severe axis deviation than exophoria. People with exotropia often experience crossed diplopia. Intermittent exotropia is a fairly common condition. "Sensory exotropia" occurs in the presence ...
Retinoblastoma (Rb) is a rare form of cancer that rapidly develops from the immature cells of a retina, [ 2] the light-detecting tissue of the eye. [ 3] It is the most common primary malignant intraocular cancer in children, especially those under 3 years old. [ 4][ 5] Though most children in high income countries survive this cancer, [ 2] they ...
Moebius syndrome. A child with oromandibular-limb hypogenesis-Möbius syndrome. Notice the expressionless face (due to bilateral VII nerve palsies) and missing fingers. Möbius syndrome or Moebius syndrome is a rare congenital neurological disorder which is characterized by facial paralysis and the inability to move the eyes from side to side.
A paraneoplastic syndrome is a syndrome (a set of signs and symptoms) that is the consequence of a tumor in the body (usually a cancerous one). [ 1] It is specifically due to the production of chemical signaling molecules (such as hormones or cytokines) by tumor cells or by an immune response against the tumor. [ 2]
Parry–Romberg syndrome ( PRS) is a rare disease presenting in early childhood [ 1] characterized by progressive shrinkage and degeneration of the tissues beneath the skin, usually on only one side of the face (hemifacial atrophy) but occasionally extending to other parts of the body. [ 2] An autoimmune mechanism is suspected, and the syndrome ...