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  2. Hypothalamic–pituitary–adrenal axis - Wikipedia

    en.wikipedia.org/wiki/Hypothalamicpituitary...

    The hypothalamic–pituitary–adrenal axis (HPA axis or HTPA axis) is a complex set of direct influences and feedback interactions among three components: the hypothalamus (a part of the brain located below the thalamus), the pituitary gland (a pea-shaped structure located below the hypothalamus), and the adrenal (also called "suprarenal ...

  3. Stress (biology) - Wikipedia

    en.wikipedia.org/wiki/Stress_(biology)

    The HPA axis is a neuroendocrine system that mediates a stress response. Neurons in the hypothalamus, particularly the paraventricular nucleus, release vasopressin and corticotropin releasing hormone, which travel through the hypophysial portal vessel where they travel to and bind to the corticotropin-releasing hormone receptor on the anterior ...

  4. Hypothalamic–pituitary–thyroid axis - Wikipedia

    en.wikipedia.org/wiki/Hypothalamicpituitary...

    The hypothalamic–pituitary–thyroid axis (HPT axis for short, a.k.a. thyroid homeostasis or thyrotropic feedback control) is part of the neuroendocrine system responsible for the regulation of metabolism and also responds to stress. As its name suggests, it depends upon the hypothalamus, the pituitary gland, and the thyroid gland.

  5. Fight-or-flight response - Wikipedia

    en.wikipedia.org/wiki/Fight-or-flight_response

    The reaction begins in the amygdala, which triggers a neural response in the hypothalamus. The initial reaction is followed by activation of the pituitary gland and secretion of the hormone ACTH. [19] The adrenal gland is activated almost simultaneously, via the sympathetic nervous system, and releases the hormone epinephrine.

  6. Neuroendocrinology - Wikipedia

    en.wikipedia.org/wiki/Neuroendocrinology

    These responses then signal back to the hypothalamus and anterior pituitary to either stop producing or continue to produce their precursor signals. Main article: Hypothalamus The hypothalamus is commonly known as the relay center of the brain because of its role in integrating inputs from all areas of the brain and producing a specific response.

  7. Pituitary gland - Wikipedia

    en.wikipedia.org/wiki/Pituitary_gland

    The pituitary gland or hypophysis is an endocrine gland in vertebrates. In humans , the pituitary gland is located at the base of the brain , protruding off the bottom of the hypothalamus . The human pituitary gland is oval shaped , about 1 cm in diameter, 0.5–1 gram (0.018–0.035 oz) in weight on average, and about the size of a kidney bean .

  8. Epigenetics of anxiety and stress–related disorders - Wikipedia

    en.wikipedia.org/wiki/Epigenetics_of_anxiety_and...

    This is significant because glucocorticoid is a regulator of the hypothalamus-pituitary-adrenal axis (HPA) and is known to affect stress response. These stress-related epigenetic changes were accompanied by other characteristics that indicated higher stress and anxiety in these offspring, including increased symptoms of PTSD, greater risk of ...

  9. Effects of stress on memory - Wikipedia

    en.wikipedia.org/wiki/Effects_of_stress_on_memory

    Diagram of the hypothalamic–pituitary–adrenal axis. The effects of stress on memory include interference with a person's capacity to encode memory and the ability to retrieve information. [1] [2] Stimuli, like stress, improved memory when it was related to learning the subject. [3]

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