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  2. Collagenase clostridium histolyticum - Wikipedia

    en.wikipedia.org/wiki/Collagenase_clostridium...

    Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum that dismantles collagen.It is used as a powder-and-solvent injection kit for the treatment of Dupuytren's contracture, a condition where the fingers bend towards the palm and cannot be fully straightened, and Peyronie's disease, a connective tissue disorder involving the growth of fibrous ...

  3. Auxilium Moves Forward on Potential Anti-Cellulite Treatment

    www.aol.com/news/2013-01-07-auxilium-moves...

    Auxilium Pharmaceuticals , a $910 million biopharmaceutical company, announced today it is expanding a license agreement with BioSpecifics Technologies giving Auxilium the right to market Xiaflex ...

  4. Dupuytren's contracture - Wikipedia

    en.wikipedia.org/wiki/Dupuytren's_contracture

    The collagenase is distributed across three injection points. [59] For the PIP joint the needle must be placed not more than 4 mm distal to palmar digital crease at 2–3 mm depth. [ 59 ] The injection for PIP consists of one injection filled with 0.58 mg CCH 0.20 ml. [ 60 ] The needle must be placed horizontal to the cord and also uses a three ...

  5. Xiaflex - Wikipedia

    en.wikipedia.org/?title=Xiaflex&redirect=no

    Collagenase clostridium histolyticum; From or to a drug trade name: This is a redirect from (or to) the trade name of a drug to (or from) ...

  6. Islet cell transplantation - Wikipedia

    en.wikipedia.org/wiki/Islet_cell_transplantation

    Researchers use a mixture of highly purified enzymes (Collagenase) to isolate islets from the pancreas of a deceased donor. Collagenase solution is injected into the pancreatic duct which runs through the head, body and tail of the pancreas. Delivered this way, the enzyme solution causes distension of the pancreas, which is subsequently cut ...

  7. How Much Does Semaglutide Cost With and Without Insurance? - AOL

    www.aol.com/much-does-semaglutide-cost-without...

    Without insurance, your semaglutide cost per month can add up. Ozempic can cost about $900 a month, Wegovy can be around $1,300 a month, and Rybelsus can cost roughly $950.

  8. Periapical cyst - Wikipedia

    en.wikipedia.org/wiki/Periapical_cyst

    Collagenase (breakdown of collagen) in the jaw bone leads to bone degeneration, providing room for cysts to develop. Substances released by the body's immune system as a result of the connective tissue breakdown, such as cytokines and growth factors, contribute to the mobilization and proliferation of epithelial cells in the area.

  9. Clostridium - Wikipedia

    en.wikipedia.org/wiki/Clostridium

    Clostridium histolyticum has been used as a source of the enzyme collagenase, which degrades animal tissue. Clostridium species excrete collagenase to eat through tissue and, thus, help the pathogen spread throughout the body. The medical profession uses collagenase for the same reason in the débridement of infected wounds. [1]

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