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  2. Zinc finger transcription factor - Wikipedia

    en.wikipedia.org/wiki/Zinc_Finger_Transcription...

    Zinc finger protein transcription factors can be encoded by genes small enough to fit a number of such genes into a single vector, allowing the medical intervention and control of expression of multiple genes and the initiation of an elaborate cascade of events. In this respect, it is also possible to target a sequence that is common to ...

  3. Zinc finger - Wikipedia

    en.wikipedia.org/wiki/Zinc_finger

    Zinc fingers were first identified in a study of transcription in the African clawed frog, Xenopus laevis in the laboratory of Aaron Klug.A study of the transcription of a particular RNA sequence revealed that the binding strength of a small transcription factor (transcription factor IIIA; TFIIIA) was due to the presence of zinc-coordinating finger-like structures. [6]

  4. ZEB1 - Wikipedia

    en.wikipedia.org/wiki/ZEB1

    Zinc finger E-box-binding homeobox 1 is a protein that in humans is encoded by the ZEB1 gene. [5] [6] [7]ZEB1 (previously known as TCF8) encodes a zinc finger and homeodomain transcription factor that represses T-lymphocyte-specific IL2 gene expression by binding to a negative regulatory domain 100 nucleotides 5-prime of the IL2 transcription start site.

  5. ZEB2 - Wikipedia

    en.wikipedia.org/wiki/ZEB2

    Zinc finger E-box-binding homeobox 2 is a protein that in humans is encoded by the ZEB2 gene. [5] The ZEB2 protein is a transcription factor that plays a role in the transforming growth factor β (TGFβ) signaling pathways that are essential during early fetal development.

  6. GATA zinc finger - Wikipedia

    en.wikipedia.org/wiki/GATA_zinc_finger

    In molecular biology, GATA zinc fingers are zinc-containing domains found in a number of transcription factors (including erythroid-specific transcription factor and nitrogen regulatory proteins). Some members of this class of zinc fingers specifically bind the DNA sequence (A/T)GATA(A/G) in the regulatory regions of genes ., [ 1 ] giving rise ...

  7. ZFPM2 - Wikipedia

    en.wikipedia.org/wiki/ZFPM2

    The zinc finger-containing protein encoded by this gene is a widely expressed member of the FOG family of regulators of transcription factors. The family consists of the ZFPM1 and ZFPM2 genes in humans and Zfpm1 and Zfpm2 genes in mice.

  8. ZFX - Wikipedia

    en.wikipedia.org/wiki/ZFX

    This gene on the X chromosome is structurally similar to a related gene on the Y chromosome ().It encodes a member of the krüppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers.

  9. ZNF16 - Wikipedia

    en.wikipedia.org/wiki/ZNF16

    Zinc finger protein 16 is a protein that in humans is encoded by the ZNF16 gene. [3] The protein encoded by this gene contains a C2H2 type of zinc finger, and thus may function as a transcription factor. This gene is located in a region close to ZNF7/KOX4, a gene also encoding a zinc finger protein, on chromosome 8. Two alternatively spliced ...