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MTAP is a phosphorylase, which is an enzyme that catalyzes the addition of an inorganic phosphate to another molecule. MTAP is responsible for the cleaving of its substrate , MTA, into adenine and 5-methylthioribose-1-phosphate by the addition of the inorganic phosphate to the 1-prime carbon of the ribose sugar unit MTA. [ 20 ]
Medical technology assessment (MTA) is the objective evaluation of a medical technology regarding its safety and performance, its (future) impact on clinical and non-clinical patient outcomes as well as its interactive effects on economical, organizational, social, juridical and ethical aspects of healthcare.