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Congenital blindness is a hereditary disease and can be treated by gene therapy. Visual loss in children or infants can occur either at the prenatal stage (during the time of conception or intrauterine period) or postnatal stage (immediately after birth). [3] There are multiple possible causes of congenital blindness.
Childhood blindness is an important contribution to the national prevalence of the disability of blindness. [3] Blindness in children can be defined as a visual acuity of <3/60 in the eye with better vision of a child under 16 years of age. [4]
The number of individuals blind from trachoma has decreased in the past 10 years from 6 million to 1.3 million, putting it in seventh place on the list of causes of blindness worldwide. Central corneal ulceration is also a significant cause of monocular blindness worldwide, accounting for an estimated 850,000 cases of corneal blindness every ...
Multiple sclerosis (MS) is an autoimmune disease resulting in damage to the insulating covers of nerve cells in the brain and spinal cord. [3] As a demyelinating disease , MS disrupts the nervous system's ability to transmit signals , resulting in a range of signs and symptoms , including physical, mental , and sometimes psychiatric problems.
Nearly 2.3 million people are estimated to be living with multiple sclerosis around the world, but when Montel Williams received his official diagnosis back in 1999, not much was known about the ...
Leber's congenital amaurosis (LCA) is the most severe and earliest of the inherited retinal dystrophies that cause congenital blindness. It has an incidence of 2-3 per 100,000 births and accounts for 10-18% of cases of congenital blindness among children in blind institutes and 5% of all retinal dystrophies, a figure that is likely to be greater in countries with a greater percentage of ...
Leber congenital amaurosis (LCA) is a rare inherited eye disease that appears at birth or in the first few months of life. [2]It affects about 1 in 40,000 newborns. [1] LCA was first described by Theodor Leber in the 19th century.
Currently it is unknown what the primary cause of MS is; if MS is a heterogeneous disease, the lesion development process would not be unique. In particular, some PPMS patients having a special clinical course named rapidly progressive multiple sclerosis could have a special genetic cause [ 47 ] and a different development process.
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