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  2. Loading dose - Wikipedia

    en.wikipedia.org/wiki/Loading_dose

    A loading dose is most useful for drugs that are eliminated from the body relatively slowly, i.e. have a long systemic half-life. Such drugs need only a low maintenance dose in order to keep the amount of the drug in the body at the appropriate therapeutic level , but this also means that, without an initial higher dose, it would take a long ...

  3. Buprenorphine - Wikipedia

    en.wikipedia.org/wiki/Buprenorphine

    Buprenorphine, sold under the brand name Subutex among others, is an opioid used to treat opioid use disorder, acute pain, and chronic pain. [18] It can be used under the tongue (sublingual), in the cheek (buccal), by injection (intravenous and subcutaneous), as a skin patch (transdermal), or as an implant.

  4. Route of administration - Wikipedia

    en.wikipedia.org/wiki/Route_of_administration

    Routes of administration are usually classified by application location (or exposition). The route or course the active substance takes from application location to the location where it has its target effect is usually rather a matter of pharmacokinetics (concerning the processes of uptake, distribution, and elimination of drugs).

  5. Booster dose - Wikipedia

    en.wikipedia.org/wiki/Booster_dose

    1964 American "Wellbee" poster promoting booster vaccines. A booster dose is an extra administration of a vaccine after an earlier dose. After initial immunization, a booster provides a re-exposure to the immunizing antigen. It is intended to increase immunity against that antigen back to protective levels after memory against that antigen has ...

  6. Bolus (medicine) - Wikipedia

    en.wikipedia.org/wiki/Bolus_(medicine)

    Diabetics and health care professionals use bolus to refer to a dosage of fast-acting insulin with a meal (as opposed to basal rate, which is a dose of slow-acting insulin or the continuous pumping of a small quantity of fast-acting insulin to cover the glucose output of the liver). [3]

  7. Subcutaneous administration - Wikipedia

    en.wikipedia.org/wiki/Subcutaneous_administration

    Subcutaneous administration is the insertion of medications beneath the skin either by injection or infusion. A subcutaneous injection is administered as a bolus into the subcutis, the layer of skin directly below the dermis and epidermis, collectively referred to as the cutis. The instruments are usually a hypodermic needle and a syringe.

  8. Intravenous therapy - Wikipedia

    en.wikipedia.org/wiki/Intravenous_therapy

    Intravenous therapy (abbreviated as IV therapy) is a medical technique that administers fluids, medications and nutrients directly into a person's vein.The intravenous route of administration is commonly used for rehydration or to provide nutrients for those who cannot, or will not—due to reduced mental states or otherwise—consume food or water by mouth.

  9. Depot injection - Wikipedia

    en.wikipedia.org/wiki/Depot_injection

    A depot injection, also known as a long-acting injectable (LAI), is a term for an injection formulation of a medication which releases slowly over time to permit less frequent administration of a medication.