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Thiamine deficiency is a medical condition of low levels of thiamine (vitamin B 1). [1] A severe and chronic form is known as beriberi. [1] [7] The name beriberi was possibly borrowed in the 18th century from the Sinhalese phrase බැරි බැරි (bæri bæri, “I cannot, I cannot”), owing to the weakness caused by the condition.
Korsakoff syndrome (KS) [1] is a disorder of the central nervous system characterized by amnesia, deficits in explicit memory, and confabulation.This neurological disorder is caused by a deficiency of thiamine (vitamin B 1) in the brain, and it is typically associated with and exacerbated by the prolonged, excessive ingestion of alcohol. [2]
Thiamine is one of the B vitamins and is also known as vitamin B 1. [1] [11] [12] It is a cation that is usually supplied as a chloride salt. [3]It is soluble in water, methanol and glycerol, but practically insoluble in less polar organic solvents.
Frequently, secondary to thiamine deficiency and subsequent cytotoxic edema in Wernicke encephalopathy, patients will have marked degeneration of the mammillary bodies. Thiamine (vitamin B 1) is an essential coenzyme in carbohydrate metabolism and is also a regulator of osmotic gradient. Its deficiency may cause swelling of the intracellular ...
Thiamine deficiency and errors of thiamine metabolism are believed to be the primary cause of Wernicke encephalopathy. Thiamine, also called B 1, helps to break down glucose. Specifically, it acts as an essential coenzyme to the TCA cycle and the pentose phosphate shunt. Thiamine is first metabolised to its more active form, thiamine ...
Adults ages 65 and older may be at a higher risk of a vitamin B deficiency, the experts say. "Sometimes older people have a harder time metabolizing food, so they might benefit from a supplement ...
Vitamin B1 deficiency (thiamine deficiency) was reported to cause seizures, especially in alcoholics. [5] [6] [7] Vitamin B6 depletion (pyridoxine deficiency) was reported to be associated with pyridoxine-dependent seizures. [8] Vitamin B12 deficiency was reported to be the cause of seizures for adults [9] [10] and for infants. [11] [12]
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