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Lupus, formally called systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. [1] Symptoms vary among people and may be mild to severe. [ 1 ]
The Centers for Disease Control and Prevention estimates that more than 200,000 people in the U.S. have lupus, though the Lupus Foundation of America puts the total much higher: roughly 1.5 ...
An estimated 5 million people worldwide have some form of lupus disease. [23] 70% of lupus cases diagnosed are systemic lupus erythematosus. [23] 20% of people with lupus will have a parent or sibling who already has lupus or may develop lupus. [23] about 5% of the children born to individuals with lupus will develop the illness. [23]
A familial tendency to develop autoimmune diseases suggests a genetic component. Some conditions, like lupus and multiple sclerosis, often occur in several members of the same family, indicating a potential hereditary link. Additionally, certain genes have been identified that increase the risk of developing specific autoimmune diseases.
Some families show genetic predisposition for these conditions, however genetics alone is often not sufficient to explain whether someone will develop an autoimmune condition. Smoking, stress, and diet can produce epigenetic modifications to the genome that alter the regulation of immune system-specific genes leading to the onset of these ...
What it looks like: Lupus, a chronic autoimmune disease that causes inflammation throughout the body, often presents with a red, butterfly-shaped rash across the cheeks and nose. It is usually ...
An immune system disorder but not autoimmune. Idiopathic giant-cell myocarditis: No consistent evidence of autoimmune cause though the disease has been found comorbid with other autoimmune diseases. [124] Idiopathic pulmonary fibrosis: Autoantibodies: SFTPA1, SFTPA2, TERT, and TERC. IgA nephropathy: An immune system disorder but not an ...
In 2022, Halsey was diagnosed with lupus SLE, a chronic disease where the body’s immune system attacks its own tissues and organs. It can damage many parts of the body, including the joints ...