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As a cream it is used for actinic keratosis, basal cell carcinoma, and skin warts. [4] [5] Side effects of use by injection are common. [3] They may include inflammation of the mouth, loss of appetite, low blood cell counts, hair loss, and inflammation of the skin. [3] When used as a cream, irritation at the site of application usually occurs. [4]
While topical 5-FU is a widely used and cost-effective treatment for AKs and is generally well tolerated, its potential side-effects can include: pain, crusting, redness, and local swelling. [55] These adverse effects can be mitigated or minimized by reducing the frequency of application or taking breaks between uses. [55]
Imiquimod is a topical immune response cream, applied to the affected area. It causes less local irritation than podofilox but may cause fungal infections (11% in package insert) and flu-like symptoms (less than 5% disclosed in package insert). [30] It does not significantly impact the occurrence of new warts or the systemic reactions. [31]
Formic acid, topical, is a common treatment for plantar warts, which works by being applied over a period of time, causing the body to reject the wart. [ 17 ] Fluorouracil cream, a chemotherapy agent sometimes used to treat skin cancer , can be used on particularly resistant warts, by blocking viral DNA and RNA production and repair.
Steroid-induced skin atrophy is thinning of the skin as a result of prolonged exposure to topical steroids. In people with psoriasis using topical steroids it occurs in up to 5% of people after a year of use. [5] Intermittent use of topical steroids for atopic dermatitis is safe and does not cause skin thinning. [6] [7] [8]
[5] [1] Another reported side effect is a gritty sensation with sexual intercourse during treatment. [2] The side effects of vaginal boric acid are usually mild and temporary. [5] The safety of topical boric acid, including its long-term safety, is under-characterized. [19] [5] [1] Boric acid has known toxic properties when taken orally or at ...
Since some topical microbicide formulations currently under development function as lubricants, such "dry sex" traditions may pose a barrier to the implementation of topical microbicidal programs. Recent data on product acceptability, however, show that many men and women enjoy using gels during sex that would contain a microbicidal drug.
Topical glucocorticoids are the topical forms of glucocorticoids. Topical glucocorticoids are used in the treatment of many skin conditions. They provide anti-inflammatory, antimitotic, and immune-system suppressing actions through various mechanisms. [1] Hydrocortisone cream is a type of topical glucocorticoid that is commonly found on the market.
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