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In the pharmaceutical industry, drug dissolution testing is routinely used to provide critical in vitro drug release information for both quality control purposes, i.e., to assess batch-to-batch consistency of solid oral dosage forms such as tablets, and drug development, i.e., to predict in vivo drug release profiles. [1]
A tablet is usually a compressed preparation that contains: 5-10% of the drug (active substance); 80% of fillers, disintegrants, lubricants, glidants, and binders; and; 10% of compounds which ensure easy disintegration, disaggregation, and dissolution of the tablet in the stomach or the intestine.
Friability and abrasion testing is performed in rotating testing drums, designed according to the pharmacopeia. The measured parameter is weight loss before and after testing and tumbling the tablets at a particular time and speed. In the friability test drum tablets are being carried up by a "shovel" and dropped.
Tilling the soil, or tillage, is the breaking of soil, such as with a plough or harrow, to prepare the soil for new seeds. Tillage systems vary in intensity and disturbance. Conventional tillage is the most intense tillage system and disturbs the deepest level of soils. At least 30% of plant residue remains on the soil surface in conservation ...
The tablet is pushed against a stationary anvil until it fractures. A reading is taken from a scale indicator. [5] Kraemer Elektronik's tablet testing system was the first automatic tablet hardness testing system for auto-regulation at tablet presses, invented by German mechanical engineer Mr. Norbert Kraemer in Darmstadt, Germany.
Phytoremediation technologies use living plants to clean up soil, air and water contaminated with hazardous contaminants. [1] It is defined as "the use of green plants and the associated microorganisms, along with proper soil amendments and agronomic techniques to either contain, remove or render toxic environmental contaminants harmless". [2]
soil type and structure. For example, sandy soil holds little water while clay soils have high water-retention rates; the amount of water used by the plants/crops; how much nitrate is already present in the soil. [3] The level of nitrous oxide (N 2 O) in the Earth's atmosphere is increasing at a rate of 0.2 to 0.3% annually.
A soil test is a laboratory or in-situ analysis to determine the chemical, physical or biological characteristics of a soil. Possibly the most widely conducted soil tests are those performed to estimate the plant-available concentrations of nutrients in order to provide fertilizer recommendations in agriculture.