Search results
Results from the WOW.Com Content Network
As per Falkow's original descriptions, the three postulates are: [1] "The phenotype or property under investigation should be associated with pathogenic members of a genus or pathogenic strains of a species. Specific inactivation of the gene(s) associated with the suspected virulence trait should lead to a measurable loss in pathogenicity or ...
Falkow is known as the father of the field of molecular microbial pathogenesis. [1] He formulated molecular Koch's postulates, which have guided the study of the microbial determinants of infectious diseases since the late 1980s. [2] Falkow spent over 50 years uncovering molecular mechanisms of how bacteria cause disease and how to disarm them. [1]
In 1988, microbiologist Stanley Falkow developed a set of three Molecular Koch's postulates for identifying the microbial genes encoding virulence factors. First, the phenotype of a disease symptom must be associated with a specific genotype only found in pathogenic strains. Second, that symptom should not be present when the associated gene is ...
Main page; Contents; Current events; Random article; About Wikipedia; Contact us; Donate
The research in his molecular spectroscopy laboratory focused on the discovery and elucidation of excitation mechanisms, with particular application to photochemical and biophysical problems. His most important achievements include identifying triplet states as source of phosphorescence emission, formulating the Kasha rule on fluorescence , and ...
Human cancer cells with nuclei (specifically the DNA) stained blue. The central and rightmost cell are in interphase, so the entire nuclei are labeled.The cell on the left is going through mitosis and its DNA has condensed.
A cycloaddition is a reaction that simultaneously forms at least two new bonds, and in doing so, converts two or more open-chain molecules into rings. [3] The transition states for these reactions typically involve the electrons of the molecules moving in continuous rings, making it a pericyclic reaction.
In 1865, German chemist August Wilhelm von Hofmann was the first to make stick-and-ball molecular models, which he used in lecture at the Royal Institution of Great Britain, such as methane shown below: Hofmann's 1865 stick-and-ball model of methane CH 4.