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Hyponatremia or hyponatraemia is a low concentration of sodium in the blood. [4] It is generally defined as a sodium concentration of less than 135 mmol/L (135 mEq/L), with severe hyponatremia being below 120 mEq/L. [3] [8] Symptoms can be absent, mild or severe.
Hypoosmolar hyponatremia is a condition where hyponatremia is associated with a low plasma osmolality. [1] The term "hypotonic hyponatremia" is also sometimes used.[2]When the plasma osmolarity is low, the extracellular fluid volume status may be in one of three states: low volume, normal volume, or high volume.
Pseudohyponatremia is a false low sodium reading that can be caused by high levels of fats or proteins in the blood. [14] [3] Dilutional hyponatremia can happen in diabetics as high glucose levels pull water into the blood stream causing the sodium concentration to be lower.
[1] [2] Low blood protein levels can result in a falsely high sodium measurement. [4] The cause can usually be determined by the history of events. [1] Testing the urine can help if the cause is unclear. [1] The underlying mechanism typically involves too little free water in the body. [6]
In this article, all values (except the ones listed below) denote blood plasma concentration, which is approximately 60–100% larger than the actual blood concentration if the amount inside red blood cells (RBCs) is negligible.
The MacArthur Study Bible, first issued in 1997 by current HarperCollins brand W Publishing, is a study Bible edited by evangelical preacher John F. MacArthur with introductions and annotations to the 66 books of the Protestant Bible.
In addition to more than 150 individual books and monographs, MacArthur has also contributed to more than 30 multi-author works. [1] His publications have been translated into more than two dozen languages, including ten or more titles each in French, Spanish, Romanian, German, Korean, Russian, Portuguese, and Italian.
It is a useful parameter in acute kidney failure and oliguria, with a value below 1% indicating a prerenal disease and a value above 1% suggesting acute tubular necrosis or other kidney damage. [6] 2956-1: Potassium (K) – per day: 40 [5] 90 [5] mmol / 24 h: Urine K may be measured in a diagnostic examination for hypokalemia (low blood