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Although the kidney cannot directly sense blood, long-term regulation of blood pressure predominantly depends upon the kidney. This primarily occurs through maintenance of the extracellular fluid compartment, the size of which depends on the plasma sodium concentration.
The mammalian kidney is the organ that has the most complex vascular blood system compared to other organs. [105] Despite their small size, the kidneys of mammals account for a significant part of the minute volume of blood circulation. [106]
These animals possess an adult kidney derived from the metanephros. [24] The duct that connects the kidney to excrete urine in these animals is the ureter. [24] In placental mammals, it connects to the urinary bladder, whence urine leaves via the urethra. [25] In monotremes, urine flows from the ureters into the cloaca. [26]
The length of the adult kidney is normally 10–12 cm, and the right kidney is often slightly longer than the left kidney. The adult kidney size is variable due to the correlation with body height and age; however, normograms for pediatric kidney size are available. [1]
The first step in urine formation is the filtration of blood in the kidneys. In a healthy human, the kidney receives between 12 and 30% of cardiac output, but it averages about 20% or about 1.25 L/min. The basic structural and functional unit of the kidney is the nephron.
The kidney takes a key role in maintenance of the constant internal environment. The relative ionic composition of the extracellular fluid is similar between marine fish and all subsequent species. Therefore, it can be said that the kidneys made it possible to preserve approximately the same composition of extracellular fluid in vertebrates as ...
What signs do appear—fatigue, anemia, swelling—don’t carry a neon sign shouting “kidney disease.” As the two fist-size organs continue to decline, the body swells—first the limbs, then ...
End-stage chronic kidney disease with increased echogenicity, homogenous architecture without visible differentiation between parenchyma and renal sinus and reduced kidney size. Measurement of kidney length on the US image is illustrated by '+' and a dashed line.