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Both vitamin D2 and D3 are good, but “D3 has better bioavailablilty,” says Dr. Manson, meaning that it’s more easily used by your body. But that doesn’t mean any old brand will do.
For example, CYP11A1, an enzyme chiefly known for its role in steroidogenesis, has been found to hydroxylate vitamin D3 at several positions, including C-20, C-22, and C-23, without cleaving the side chain. The resulting metabolites, such as 20-hydroxyvitamin D3 and 20,23-dihydroxyvitamin D3, act as inverse agonists for RORα and RORγ2.
Vitamin K2 may have a protective effect on bone mineral density and reduced risk of hip, vertebral and non-vertebral fractures. [11] These effects appear to be accentuated when combined with vitamin D and in the setting of osteoporosis. [1] Research suggests that vitamin K 2 (Menaquinone 7, MK-7]) may reduce the rate and severity of night time ...
There's lots of confusion around the difference between vitamin D2 and vitamin D3, and which is best for whom. Doctors and experts explain.
Cholecalciferol is a form of vitamin D which is naturally synthesized in skin and functions as a pro-hormone, being converted to calcitriol.This is important for maintaining calcium levels and promoting bone health and development. [4]
Vitamin D (the inactive version) is mainly from two forms: vitamin D 3 and vitamin D 2.Vitamin D 3, or cholecalciferol, is formed in the skin after exposure to sunlight or ultra violet radiation or from D 3 supplements or fortified food sources.
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