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Fenamic acid is a derivative of anthranilic acid, [18]: 235 which in turn is a nitrogen isostere of salicylic acid, which is the active metabolite of aspirin. [ 18 ] : 235 Several non-steroidal anti-inflammatory drugs , including mefenamic acid , tolfenamic acid , flufenamic acid , and meclofenamic acid are derived from fenamic acid or ...
Methyl anthranilate, also known as MA, methyl 2-aminobenzoate, or carbomethoxyaniline, is an ester of anthranilic acid. Its chemical formula is C 8 H 9 NO 2. It has a strong and fruity grape smell, and one of its key uses is as a flavoring agent.
Anthranilic acid, its esters, and its salts methaqualone and analogues Benzyl cyanide: phenylacetic acid, phenylacetone, amphetamine: Ephedrine, its salts, optical isomers, and salts of optical isomers methamphetamine: Ergonovine and its salts lysergic acid diethylamide: Ergotamine and its salts lysergic acid diethylamide
Mefenamic acid is a member of the anthranilic acid derivatives (or fenamate) class of nonsteroidal anti-inflammatory drugs (NSAIDs), and is used to treat mild to moderate pain. [4] [5] Its name derives from its systematic name, dimethylphenylaminobenzoic acid. It was discovered and brought to market by Parke-Davis as Ponstel in the 1960s.
The following NSAIDs are derived from fenamic acid, which is a derivative of anthranilic acid, [143]: 235 which in turn is a nitrogen isostere of salicylic acid, which is the active metabolite of aspirin. [143]: 235 [144]: 17
N-Acetylanthranilic acid can be synthesized from 2-bromoacetanilide via palladium-catalyzed carbonylation in tri-n-butylamine-water at 110–130 °C, under 3 atm of carbon monoxide. [4] In the laboratory, it can be easily synthesized from anthranilic acid and acetic anhydride. N-Acetylanthranilic acid exhibits triboluminescence when crushed. [5]
Diamide insecticides are a class of insecticides, active mainly against lepidoptera (caterpillars), which act on the insect ryanodine receptor.They are diamides of either phthalic acid or anthranilic acid, with various appropriate further substitutions.
Anthranilate-based insect repellents include methyl anthranilate, N,N-dimethylanthranilic acid (DMA), ethyl anthranilate (EA), and butyl anthranilate (BA). Chemically, they are esters of anthranilic acid.