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The medial longitudinal fasciculus is the main central connection for the oculomotor nerve, trochlear nerve, and abducens nerve. It carries information about the direction that the eyes should move. Lesions of the medial longitudinal fasciculus can cause nystagmus and diplopia, which may be associated with multiple sclerosis, a neoplasm, or a ...
It is located anterior and lateral to the medial longitudinal fasciculus. [citation needed] It is continuous caudally with the nucleus prepositus hypoglossi. [4] The PPRF (and adjacent regions of the pons) are traversed by fibers projecting to the abducens nucleus that mediate smooth pursuit, vestibular reflexes, and gaze holding. [5]: 498
The medial vestibulospinal tract projects bilaterally from the medial vestibular nucleus within the medial longitudinal fasciculus to the ventral horns in the upper cervical cord (C6 vertebra). [5] It promotes stabilization of head position by innervating the neck muscles, which helps with head coordination and eye movement.
It descends through the medulla oblongata near the midline within the medial longitudinal fasciculus. [1] In the spinal cord, it descends in the anterior funiculus. [1] It terminates by synapsing with interneurons of the intermediate zone and anterior grey column. [1]
Diagram showing a few of the connections of afferent (sensory) fibers of the posterior root with the efferent fibers from the ventral column and with the various long ascending fasciculi. (Spinotectal fasciculus labeled at bottom right.)
the ascending branches send terminals and collaterals to the motor nuclei of the abducens, trochlear and oculomotor nerves via the ascending component of the medial longitudinal fasciculus, and are concerned in coordinating the movements of the eyes with alterations in the position of the head;
The Edinger–Westphal nucleus refers to the adjacent population of non-preganglionic neurons that do not project to the ciliary ganglion, but rather project to the spinal cord, dorsal raphe nucleus, lateral septal nuclei, lateral hypothalamic area and the central nucleus of the amygdala, among other regions.
The middle layer consists of nerve cells and nerve fibers; fibers enter it from the parietal lobe through the external capsule, while others are said to connect it with the medial longitudinal fasciculus. The inferior layer forms the main part of the inferior stalk of the thalamus, and connects this body with the temporal lobe and the insula.