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Although most mutations of MSI are the result of frame-shift mutations, occasionally the mutation events leading to MSI are derived from the hypermethylation of the hMLH1 (MMR protein) promoter. Hypermethylation occurs when a methyl group is added to a DNA nucleotide, resulting in gene silencing, thus yielding MSI.
DNA mismatch repair (MMR) is a system for recognizing and repairing erroneous insertion, deletion, and mis-incorporation of bases that can arise during DNA replication and recombination, as well as repairing some forms of DNA damage.
House remembers a baby he treated earlier whose mother did not want to vaccinate the child and hypothesizes that infant Dan may have caught the measles virus, which remained latent for 16 years. Avoiding a dangerous procedure to confirm this unusual case, they biopsy Dan's retina to find the virus, confirming House's diagnosis of subacute ...
The episode is set from the viewpoint of House and Dr. Nolan (guest star Andre Braugher), looking into House's past week to try to work out why House is showing signs of being upset and unperceptive. During the session with Dr. Nolan, House recounts the case of a woman (guest star Zoe McLellan ) who arrives at the Princeton Plainsboro emergency ...
Fox News medical contributor Dr. Nicole Saphier addresses frequently asked questions regarding the measles, mumps and rubella (MMR) vaccine, covering side effects, autism and more.
House, also known as House, M.D., is an American medical drama series which premiered on Fox on November 16, 2004. House was created by David Shore. The show follows Dr. Gregory House (Hugh Laurie), an irascible, maverick medical genius who heads a team of diagnosticians at the fictional Princeton-Plainsboro Teaching Hospital (PPTH) in New Jersey.
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The Tennessee House of Representatives 15th District covers the center of Knox County, including downtown and South Knoxville. It’s been represented by a Democrat since at least 1988. Tennessee ...