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Non-small cell lung cancer, oesophageal cancer, uterine cervical cancer, head and neck cancer and urothelial cancer: Nephrotoxicity, myelosuppression and nausea and vomiting (30-90%). Oxaliplatin: IV: Reacts with DNA, inducing apoptosis, non-cell cycle specific. Colorectal cancer, oesophageal cancer and gastric cancer
In females, the paramesonephric ducts give rise to the uterine tubes, uterus, and upper portion of the vagina, while the mesonephric ducts degenerate due to the absence of male androgens. In contrast, the paramesonephric ducts begin to proliferate and differentiate in a cranial-caudal progression to form the aforementioned structures.
This is a list of chemotherapeutic agents, also known as cytotoxic agents or cytostatic drugs, that are known to be of use in chemotherapy for cancer.This list is organized by type of agent, although the subsections are not necessarily definitive and are subject to revision.
The Müllerian ducts are also referred to as paramesonephric ducts, referring to ducts next to (para) the mesonephric (Wolffian) duct during foetal development. Paramesonephric ducts are paired ducts derived from the embryo, and for females develop into the uterus , uterine tubes , cervix and upper two-thirds of the vagina. [ 6 ]
268 11705 Ensembl ENSG00000104899 ENSMUSG00000035262 UniProt P03971 P27106 Q5EC55 RefSeq (mRNA) NM_000479 NM_007445 RefSeq (protein) NP_000470 NP_031471 Location (UCSC) Chr 19: 2.25 – 2.25 Mb Chr 10: 80.64 – 80.64 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Anti-Müllerian hormone (AMH), also known as Müllerian-inhibiting hormone (MIH), is a glycoprotein hormone structurally ...
In females, the mesonephros degenerates entirely, though vestigial structures such as Gartner's ducts, the epoophoron, and paroophoron are common. In males, a few of the more caudal tubules will survive and give rise to the efferent ductules of the testis , [ 1 ] the epididymis , vas deferens , seminal vesicle , as well as vestigial structures ...
The prostatic utricle is a remnant that is homologous to the female uterus (including the cervix) and vagina, usually described as derived from the paramesonephric ducts, [9] although this is occasionally disputed. [10]
The fetus has two sets of tubes which give rise to accessory reproductive organs - the (Wolffian) mesonephric ducts and the (Müllerian) paramesonephric ducts. Usually, the Wolffian duct gives rise to male reproductive organs (specifically the testicle, epididymis and vas deferens) while the Müllerian to female (the fallopian tubes, the uterus ...