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Xerostomia, also known as dry mouth, is a subjective complaint of dryness in the mouth, which may be associated with a change in the composition of saliva, or reduced salivary flow, or have no identifiable cause. [1] This symptom is very common and is often seen as a side effect of many types of medication.
Known side effects include nausea, vomiting, diarrhea, excessive sweating, rash, headache, runny nose, cough, drowsiness, hot flashes, blurred vision, and difficulty sleeping. [3] Contraindications include asthma and angle closure glaucoma. [citation needed]
Xerostomia itself has many possible causes, but commonly the cause may be side effects of medications, or conditions such as Sjögren's syndrome. Conversely, conditions which cause drooling or sialorrhoea (excessive salivation) can cause angular cheilitis by creating a constant wet environment in the corners of the mouth.
Artificial saliva is primarily used to relieve symptoms of xerostomia, known as dry mouth and hyposalivation, which is a condition that results in reduced saliva production. Various factors, including medication use, cancer therapy , and certain diseases, such as diabetes , stroke or Sjögren syndrome , can cause xerostomia. [ 1 ]
Bradycardia; Hypertension (high blood pressure); Allergic reactions (e.g. dyspnoea (shortness of breath), bronchospasm, wheezing, angioneurotic oedema) Anaphylaxis; Changes in appetite
Hydrocortisone is a corticosteroid that is clinically used to relieve the pain and discomfort of mouth ulcers and functions to speed the healing of mouth ulcers. [citation needed] Common side effects include: oral thrush, visual disturbances (e.g. blurry vision), worsening of diabetes, worsening of mouth infections, and allergic reactions (e.g. skin rash).
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Patients who stayed on the medication had an average of 11% greater reduction in depressive symptoms than placebo in an FDA approval trial. [2] [3] It is taken as a tablet by mouth. [1] Side effects of dextromethorphan/bupropion include dizziness, headache, diarrhea, somnolence, dry mouth, sexual dysfunction, and hyperhidrosis, among others. [1]
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