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Altitude acclimatization is the process of adjusting to decreasing oxygen levels at higher elevations, in order to avoid altitude sickness. [17] Once above approximately 3,000 metres (10,000 ft) – a pressure of 70 kilopascals (0.69 atm) – most climbers and high-altitude trekkers take the "climb-high, sleep-low" approach.
High-altitude pulmonary edema (HAPE) is a life-threatening form of non-cardiogenic pulmonary edema that occurs in otherwise healthy people at altitudes typically above 2,500 meters (8,200 ft). [2] HAPE is a severe presentation of altitude sickness. Cases have also been reported between 1,500–2,500 metres or 4,900–8,200 feet in people who ...
Acetazolamide is an inhibitor of carbonic anhydrase.It is used for glaucoma, epilepsy (rarely), idiopathic intracranial hypertension, and altitude sickness. For the reduction of intraocular pressure (IOP), acetazolamide inactivates carbonic anhydrase and interferes with the sodium pump, which decreases aqueous humor formation and thus lowers IOP.
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It is used in the treatment of glaucoma, drug-induced edema, heart failure-induced edema, epilepsy and in reducing intraocular pressure after surgery. [9] [10] It has also been used in the treatment of altitude sickness, [11] Ménière's disease, increased intracranial pressure and neuromuscular disorders. [12]
The news agency identified 10 patent filings that list six of WuXi AppTec's staff as co-inventors of altitude sickness drugs with six scientists from the PLA General Hospital in Beijing - China's ...
Mountain Sickness. Beyond a massive adrenaline rush, mountain climbing can come with a bout of altitude sickness, sometimes called mountain sickness.
Dexamethasone is used in the treatment of high-altitude cerebral edema (HACE), as well as high-altitude pulmonary edema (HAPE). [59] It is commonly carried on mountain-climbing expeditions to help climbers deal with complications of altitude sickness. [60] [61]
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