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Though there is no set maximum concentration (maximum contaminant level, MCL) for metolachlor that is allowed in drinking water, the US EPA does have a health advisory level (HAL) of 0.525 mg/L. Metolachlor has been detected in ground and surface waters in concentrations ranging from 0.08 to 4.5 parts per billion (ppb) throughout the U.S. [9]
4-Chloroaniline is used in the industrial production of pesticides, drugs, and dyestuffs. It is a precursor to the widely used antimicrobial and bacteriocide chlorhexidine and is used in the manufacture of pesticides, including pyraclostrobin, anilofos, monolinuron, and chlorphthalim.
2,5-Dimethoxy-4-chloroamphetamine (DOC) is a psychedelic drug of the phenethylamine, amphetamine, and DOx families. It was presumably first synthesized by Alexander Shulgin , and was described in his book PiHKAL ( Phenethylamines i Have Known And Loved ).
The Food and Drug Administration (FDA) recently approved the nasal spray Spravato for the treatment of major depression in people who have not responded to at least two oral antidepressants.
In February 1998, the South African Pharmaceutical Manufactures Association and forty Multinational Corporations (MNC) brought a suit against the government of South Africa for its passage of the Medicines and Related Substances Control Amendment Act No. 90 of 1997, arguing that it violated the Agreement on Trade-Related Aspects of Intellectual Property Rights.
4-Chloromethcathinone (also known as 4-CMC and clephedrone) is a stimulant drug of the cathinone class that has been sold online as a designer drug. [ 1 ] [ 2 ] 4-CMC produces similar effects to mephedrone , and has been sold as an alternative in countries where mephedrone was scheduled.
In ortho-substitution, two substituents occupy positions next to each other, which may be numbered 1 and 2.In the diagram, these positions are marked R and ortho.; In meta-substitution, the substituents occupy positions 1 and 3 (corresponding to R and meta in the diagram).
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