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Hydrochlorothiazide, sold under the brand name Hydrodiuril among others, is a diuretic medication used to treat hypertension and swelling due to fluid build-up. [4] Other uses include treating diabetes insipidus and renal tubular acidosis and to decrease the risk of kidney stones in those with a high calcium level in the urine. [4]
Its effects are opposite that of a diuretic. The major endogenous antidiuretics are antidiuretic hormone (ADH; also called vasopressin) and oxytocin. Both of those are also used exogenously as medications in people whose bodies need extra help with fluid balance via suppression of diuresis.
Canagliflozin, sold under the brand name Invokana among others, is a medication used to treat type 2 diabetes. [3] It is used together with exercise and diet. [3] It is not recommended in type 1 diabetes. [3] It is taken by mouth. [3] Common side effects include vaginal yeast infections, nausea, constipation, and urinary tract infections. [3]
The drug was discovered as part of a screening process of chemicals that reversed the effects of mineralocorticoids in vivo. [27] Amiloride was the only drug in the screen that was capable of causing the excretion of sodium (natriuresis) without a concomitant urinary excretion of potassium (kaliuresis). [27]
There are several categories of diuretics. All diuretics increase the excretion of water from the body, through the kidneys. There exist several classes of diuretic, and each works in a distinct way. Alternatively, an antidiuretic, such as vasopressin (antidiuretic hormone), is an agent or drug which reduces the excretion of water in urine.
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The combination is available in a number of products from various brands under different names. The dosages are essentially the same for each brand, including generic drug store varieties. A diuretic is also used to reduce edema (fluid buildup) in the body. Edema can cause swelling of the extremities, such as in the hands and feet.
Top Prescription Weight Loss Pills. Anti-obesity medications (AOMs) date back to the 1940s — well before modern regulations from the FDA (U.S. Food and Drug Administration) (FDA) were in place ...
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