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Triple-negative breast cancer comprises 15–20% of all breast cancer cases [3] and affects more young women or women with a mutation in the BRCA1 gene than other breast cancers. [4] Triple-negative breast cancers comprise a very heterogeneous group of cancers. TNBC is the most challenging breast cancer type to treat. [5]
Because many symptoms of cancer are gradual in onset and general in nature, cancer screening (also called cancer surveillance) is a key public health priority. This may include laboratory work, physical examinations, tissue samples, or diagnostic imaging tests that a community of experts recommends be conducted at set intervals for particular ...
Breast cancer predominantly affects women; less than 1% of those with breast cancer are men. [158] Women can develop breast cancer as early as adolescence, but risk increases with age, and 75% of cases are in women over 50 years old. [158] The risk over a woman's lifetime is approximately 1.5% at age 40, 3% at age 50, and more than 4% risk at ...
Inflammatory breast cancer [1] (IBC) is one of the most aggressive types of breast cancer. It can occur in women of any age (and, extremely rarely, in men, see male breast cancer [ 2 ] ). It is referred to as "inflammatory" due to its frequent presentation with symptoms resembling a skin inflammation, such as erysipelas .
Men with breast cancer have an absolute risk of presenting with a second cancer in their other breast of 1.75, i.e. they have a 75% increase of developing a contralateral breast cancer over their lifetimes compared to men who develop a breast cancer without having had a prior breast cancer. [5]
A feeling of pressure and squeezing in the chest is a serious indication that medical care is essential because chest pain and discomfort is one of the most common symptoms of heart attack in men.
Symptomatic features of paraneoplastic syndrome cultivate in four ways: endocrine, neurological, mucocutaneous, and hematological.The most common presentation is a fever (release of endogenous pyrogens often related to lymphokines or tissue pyrogens), but the overall picture will often include several clinical cases observed which may specifically simulate more common benign conditions.
Post-mastectomy pain syndrome is a chronic neuropathic pain that usually manifests as continuous pain in the arm, axilla, chest wall, and breast region. [3] Pain is most likely to start after surgery, [3] although adjuvant therapy, such as chemotherapy or radiation therapy, may sometimes cause new symptoms to appear. [4]