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  2. Immunohistochemistry - Wikipedia

    en.wikipedia.org/wiki/Immunohistochemistry

    This led to the later development of immunohistochemistry. [2] [3] Immunohistochemical staining is widely used in the diagnosis of abnormal cells such as those found in cancerous tumors. In some cancer cells certain tumor antigens are expressed which make it possible to detect.

  3. Immunostaining - Wikipedia

    en.wikipedia.org/wiki/Immunostaining

    Clinically, IHC is used in histopathology for the diagnosis of specific types of cancers based on molecular markers. [ citation needed ] In laboratory science, immunostaining can be used for a variety of applications based on investigating the presence or absence of a protein, its tissue distribution, its sub-cellular localisation, and of ...

  4. Histopathologic diagnosis of prostate cancer - Wikipedia

    en.wikipedia.org/wiki/Histopathologic_diagnosis...

    A histopathologic diagnosis of prostate cancer is the discernment of whether there is a cancer in the prostate, as well as specifying any subdiagnosis of prostate cancer if possible. The histopathologic subdiagnosis of prostate cancer has implications for the possibility and methodology of any subsequent Gleason scoring. [1]

  5. Anatomical pathology - Wikipedia

    en.wikipedia.org/wiki/Anatomical_pathology

    Its use has been largely supplanted by immunohistochemistry, but it is still in common use for certain tasks, including the diagnosis of kidney disease and the identification of immotile cilia syndrome. Tissue cytogenetics – the visualization of chromosomes to identify genetic defects such as chromosomal translocation

  6. Atypical teratoid rhabdoid tumor - Wikipedia

    en.wikipedia.org/wiki/Atypical_teratoid_rhabdoid...

    Immunohistochemistry for INI1, the product of the SMARCB1 gene typically defective in AT/RT: Note the loss of brown staining in the nuclei of tumor cells with defective SMARCB1 as compared to retained staining of nuclei of vascular cells (internal positive control). Immunohistochemical staining is widely used in the diagnosis and treatment of ...

  7. AE1/AE3 - Wikipedia

    en.wikipedia.org/wiki/AE1/AE3

    AE1/AE3 is an antibody cocktail that is used in immunohistochemistry, being generally positive in the cytoplasm of carcinomas (cancers of epithelial origin). [ 1 ] [ 2 ] Targets

  8. Non-Hodgkin lymphoma - Wikipedia

    en.wikipedia.org/wiki/Non-Hodgkin_lymphoma

    If cancer is found, the following tests may be done to study the cancer cells: Immunohistochemistry. Cytogenetic analysis. Immunophenotyping. Other tests and procedures may be done depending on the signs and symptoms seen and where the cancer forms in the body. [10] [11]

  9. Gastrointestinal stromal tumor - Wikipedia

    en.wikipedia.org/wiki/Gastrointestinal_stromal_tumor

    Negative immunohistochemistry staining for β-catenin in cell nuclei is a ... differential diagnosis and targeted cancer therapy with Imatinib" (PDF ...

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