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Dulaglutide, sold under the brand name Trulicity among others, [8] is a medication used for the treatment of type 2 diabetes in combination with diet and exercise. [9] [10] It is also approved in the United States for the reduction of major adverse cardiovascular events in adults with type 2 diabetes who have established cardiovascular disease or multiple cardiovascular risk factors.
It is also possible that they provide additive cardioprotective effects. [13] The FDA has not approved GLP-1 agonists for type 1 diabetes, but they can be used off-label in addition to insulin to help type 1 diabetes patients improve their body weight and glucose control. [8]
Victoza is FDA-approved to treat type 2 diabetes but is also sometimes prescribed off-label for weight loss. Saxenda is FDA-approved for weight management in people with obesity. 3.
Drugs used in diabetes treat types of diabetes mellitus by decreasing glucose levels in the blood.With the exception of insulin, most GLP-1 receptor agonists (liraglutide, exenatide, and others), and pramlintide, all diabetes medications are administered orally and are thus called oral hypoglycemic agents or oral antihyperglycemic agents.
Insulin resistance is when your tissues no longer adequately respond to insulin to lower blood glucose levels. Glucose is the sugar molecule your body uses for energy. Insulin is produced by beta ...
Alogliptin (FDA approved 2013 as Nesina/ Vipidia, marketed by Takeda Pharmaceutical Company) Trelagliptin (approved for use in Japan as Zafatek/ Wedica in 2015) Omarigliptin (MK-3102) (approved as Marizev in Japan in 2015, [ 12 ] developed by Merck & Co. ; research showed that omarigliptin can be used as once-weekly treatment and generally well ...
The first medication in this class, sitagliptin, received FDA approval in 2006 for the treatment of type 2 diabetes mellitus. The GLP-1 analogs principally act as agonists of the GLP-1 receptor and are thus insulinotropic. Exenatide was the first drug in this class to be used in the treatment of type 2 diabetes; it first received FDA approval ...
Sotagliflozin (Inpefa) is a dual SGLT1/SGLT2 inhibitor approved by the US Food and Drug Administration (FDA) in May 2023, to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes, chronic kidney disease, and other cardiovascular risk factors.
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