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[82] [83] Memantine and amantadine are said to have moderate anti-akinetic effects in the treatment of Parkinson's disease. [78] [88] The doses of memantine used for Parkinson's disease are about 5- to 10-fold lower than those of amantadine, which has been attributed to greater potency of memantine. [78]
In various studies, amantadine and memantine have been shown to accelerate the rate of recovery from a brain injury. [ 33 ] [ 34 ] The time-limited window following a brain injury is characterized by neuroplasticity , or the capacity of neurons in the brain to adapt and compensate after injury.
It is a derivative of amantadine which was first an anti-influenza agent but was later discovered by coincidence to have efficacy in Parkinson's disease. Chemical structures of memantine and amantadine can be seen in figure 5. The compound was first thought to be dopaminergic or anticholinergic but was later found to be an NMDA receptor antagonist.
Rimantadine, like its antiviral cousin amantadine, possesses antiparkinsonian activity and can be used in the treatment of Parkinson's disease. [12] [13] However, in general, neither rimantadine nor amantadine is a preferred agent for this therapy and would be reserved for cases of the disease that are less responsive to front-line treatments.
Memantine (Namenda) - treats Dementia and Alzheimer's. N. Neurontin – an anticonvulsant which is sometimes used as a mood stabilizer, anti-anxiety agent or to ...
Mounjaro vs. Ozempic: Which Is Better for Weight Loss? This article was reviewed by Craig Primack, MD, FACP, FAAP, FOMA. They’re both once-a-week injectable drugs designed to help patients with ...
NMDA receptor antagonists induce a state called dissociative anesthesia, marked by catalepsy, amnesia, and analgesia. [1] Ketamine is a favored anesthetic for emergency patients with unknown medical history and in the treatment of burn victims because it depresses breathing and circulation less than other anesthetics.
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related to: amantadine vs memantine- 109 S High St #100, Columbus, OH · Directions · (614) 224-4261
