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Dieldrin is an organochlorine compound originally produced in 1948 by J. Hyman & Co, Denver, as an insecticide. Dieldrin is closely related to aldrin , which reacts further to form dieldrin. Aldrin is not toxic to insects; it is oxidized in the insect to form dieldrin which is the active compound.
The aldrin and dieldrin treatment demonstrated a decrease of 75 times less chiggers on rats for dieldrin treated terrains and 25 times less chiggers on the rats when treated with aldrin. The aldrin treatment indicate a high productivity, especially in comparison to other insecticides that were used at the time, such as DDT, sulfur or lindane. [20]
The mechanism of action is the insecticide binding at the GABA A site in the GABA-gated chloride channel (IRAC group 2A), which inhibits chloride flow into the nerve. [13]: 257 Other examples include dicofol, mirex, kepone, and pentachlorophenol. These can be either hydrophilic or hydrophobic, depending on their molecular structure. [14]
Other members of the cyclodiene family of organochlorine insecticides are aldrin and its epoxide, dieldrin, as well as endrin, which is a stereoisomer of dieldrin. Cyclodiene derives its name from hexachlorocyclopentadiene, a precursor in its production. Synthesis of cis- (above) and trans-chlordane (below)
Dieldrin residues have been found in air, water, soil, fish, birds, and mammals. Human exposure to dieldrin primarily derives from food. Endrin, an insecticide sprayed on the leaves of crops, and used to control rodents. Animals can metabolize endrin, so fatty tissue accumulation is not an issue, however the chemical has a long half-life in ...
A pesticide poisoning occurs when pesticides, chemicals intended to control a pest, ... The organochlorine pesticides, like DDT, aldrin, and dieldrin, are extremely ...
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