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The ingestion of neem oil is potentially toxic and can cause metabolic acidosis, seizures, kidney failure, encephalopathy and severe brain ischemia in infants and young children. [ 2 ] [ 8 ] [ 9 ] Neem oil should not be consumed alone without any other solutions, particularly by pregnant women, women trying to conceive or children. [ 2 ]
Azadirachtin, a chemical compound belonging to the limonoid group, is a secondary metabolite present in neem seeds. It is a highly oxidized tetranortriterpenoid which boasts a plethora of oxygen-bearing functional groups, including an enol ether , acetal, hemiacetal , tetra-substituted epoxide and a variety of carboxylic esters .
Azadirachta indica, commonly known as neem, margosa, nimtree or Indian lilac, [3] is a tree in the mahogany family Meliaceae. It is one of the two species in the genus Azadirachta . It is native to the Indian subcontinent and to parts of Southeast Asia , but is naturalized and grown around the world in tropical and subtropical areas.
In the USA 13 are registered for use, in the EU 6. In Korea, where it is easier to register botanical pesticides, 38 are used. Most used are neem oil, chenopodium, pyrethrins, and azadirachtin. [49] Many botanical insecticides used in past decades (e.g. rotenone, nicotine, ryanodine) have been banned because of their toxicity. [49]
The ban on cosmetic lawn pesticides started from municipalities regulating their use, which then spread across the province and onwards. The Quebec government was the first province to regulate the use and sale of cosmetic pesticides in April 2003, when it introduced the Quebec Pesticides Management Code.
Synthetic repellents tend to be more effective and/or longer lasting than "natural" repellents. [1] [2]For protection against ticks and mosquito bites, the U.S. Centers for Disease Control (CDC) recommends DEET, icaridin (picaridin, KBR 3023), oil of lemon eucalyptus (OLE), para-menthane-diol (PMD), IR3535 and 2-undecanone with the caveat that higher percentages of the active ingredient ...
Azadirachta is a genus of two species of trees in the mahogany family Meliaceae. [2] Numerous species have been proposed for the genus but only two are currently recognized, Azadirachta excelsa and the economically important tree Azadirachta indica, the neem tree, from which neem oil is extracted.
This molecule can also be found in neem oil at 0.12%. [3] Among the metabolites present in neem, nimbin is the least present chemical compound. [15] Nimbin biosynthesis is not influenced by environmental conditions [17] (temperature, rainfall, humidity…) because neem trees from the same agro-climatic zone can have very different nimbin ...
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