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Surgery is curative for benign tumors, and likely curative for other low grade tumors. Benign serous tumors include serous cystadenomas, cystadenofibromas, and adenofibromas. Benign and borderline serous tumours are commonly unilocular. Benign tumors contain clear fluid and have a smooth lining composed of columnar epithelial cells with cilia ...
They contain serous acini, a grouping of serous cells that secrete serous fluid, isotonic with blood plasma, that contains enzymes such as alpha-amylase. Serous glands are most common in the parotid gland and lacrimal gland but are also present in the submandibular gland and, to a far lesser extent, the sublingual gland.
Acinic cell carcinoma is a malignant tumor representing 2% of all salivary tumors. 90% of the time found in the parotid gland, 10% intraorally on buccal mucosa or palate. The disease presents as a slow growing mass, associated with pain or tenderness in 50% of the cases.
Submucosal means that the actual gland resides in the connecting tissue below the mucosa. The submucosa is the tissue that connects the mucosa to the muscle outside the tube. The glands themselves are quite complex. The mucus factory is at the bottom, in the submucosa, it is composed of many little sacs (acini) where the mucus originates.
The tumor may be in the form of a hard plaque or a papule, often with an opalescent quality, with tiny blood vessels; The tumor can lie below the level of the surrounding skin, and eventually ulcerates and invades the underlying tissue; The tumor commonly presents on sun-exposed areas (e.g. back of the hand, scalp, lip, and superior surface of ...
After sectioning the serous cells resembled the common demilune shape, and were so named. [2] When the gland has this demilunar structure, it has mucoserous acini producing both serous and mucous secretions. Slice of submandibular gland. H&E staining, the structure of the red stained cytoplasm on the left is the serous demilunes.
Skin cancer is the most commonly diagnosed form of cancer in humans. [11] [12] [13] There are three main types of skin cancers: basal-cell skin cancer (BCC), squamous-cell skin cancer (SCC) and melanoma. [1] The first two, along with a number of less common skin cancers, are known as nonmelanoma skin cancer (NMSC).
Basal-cell cancer is a very common skin cancer. It is much more common in fair-skinned individuals with a family history of basal-cell cancer and increases in incidence closer to the equator or at higher altitude. It is very common among elderly people over the age of 80. [63]