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Sodium butyrate is a compound with formula Na(C 3 H 7 COO). It is the sodium salt of butyric acid . It has various effects on cultured mammalian cells including inhibition of proliferation , induction of differentiation and induction or repression of gene expression. [ 1 ]
Imiquimod (Aldara) has been used with success for squamous-cell carcinoma in situ of the skin and the penis, but the morbidity and discomfort of the treatment is severe. An advantage is the cosmetic result: after treatment, the skin resembles normal skin without the usual scarring and morbidity associated with standard excision.
In particular, butyrate inhibits colonic tumor cells and stimulates proliferation of healthy colonic epithelial cells. [ 70 ] [ 71 ] The explanation why butyrate is an energy source for normal colonocytes and induces apoptosis in colon cancer cells, is the Warburg effect in cancer cells, which leads to butyrate not being properly metabolized.
Chaparral (or Larrea tridentata) – a plant used to make a herbal remedy which is sold as cancer treatment. Cancer Research UK state that: "We don't recommend that you take chaparral to treat or prevent any type of cancer." [67] Chlorella – a type of algae promoted for its health-giving properties, including a claimed ability to treat cancer ...
Contains ingenol mebutate (Picato) which is used to treat skin cancer [9] Maytenus ovatus. Trastuzumab emtansine (Kadcyla) is an antibody conjugated to a synthetic derivative of the cytotoxic principle of the Ethiopian plant Maytenus ovatus. It used to treat breast cancer. [10] Mappia foetida
The primary cause of skin cancer is prolonged exposure to ultraviolet (UV) radiation from the sun or tanning devices. Skin cancer is the most commonly diagnosed form of cancer in humans. [11] [12] [13] There are three main types of skin cancers: basal-cell skin cancer (BCC), squamous-cell skin cancer (SCC) and melanoma. [1]
Basal-cell carcinoma (BCC), also known as basal-cell cancer, basalioma [7] or rodent ulcer, [8] is the most common type of skin cancer. [2] It often appears as a painless raised area of skin, which may be shiny with small blood vessels running over it . [ 1 ]
There are a few possible causes of resistance in cancer, one of which is the presence of small pumps on the surface of cancer cells that actively move chemotherapy from inside the cell to the outside. Cancer cells produce high amounts of these pumps, known as p-glycoprotein, in order to protect themselves from chemotherapeutics. Research on p ...
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