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The dermatome is the dorsal portion of the paraxial mesoderm somite which gives rise to the skin . In the human embryo, it arises in the third week of embryogenesis . [ 2 ] It is formed when a dermomyotome (the remaining part of the somite left when the sclerotome migrates), splits to form the dermatome and the myotome. [ 2 ]
[4] [5] However, the segmentation clock model is highly evolutionarily conserved. [ 6 ] Intrinsic expression of "clock genes" must oscillate with a periodicity equal to the time necessary for one somite to form, for example 30 minutes in zebrafish, 90 minutes in chicks, and 100 minutes in snakes.
The notochord and the neural tube activate the protein SHH, which helps the somite to form its sclerotome. The cells of the sclerotome express the protein PAX1 that induces the cartilage and bone formation. The neural tube activates the protein WNT1 that expresses PAX 2 so the somite creates the myotome and dermatome.
Paraxial mesoderm, also known as presomitic or somitic mesoderm, is the area of mesoderm in the neurulating embryo that flanks and forms simultaneously with the neural tube. ...
Following is a list of spinal nerves and points that are characteristically belonging to the dermatome of each nerve: [4] Dermatomes of the lower limb (modified, from Fender, after Foerster) C2 – At least one cm lateral to the occipital protuberance at the base of the skull. Alternately, a point at least 3 cm (1.2 in) behind the ear.
Sclerotome. 4 languages ... Download as PDF; Printable version; In other projects Wikidata item; Appearance. ... This page was last edited on 4 December 2022, at 05: ...
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Similarly a dermatome is an area of skin that a single nerve innervates with sensory fibers. Myotomes are separated by myosepta (singular: myoseptum ). [ 2 ] In vertebrate embryonic development , a myotome is the part of a somite that develops into muscle.