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  2. Ibuprofen - Wikipedia

    en.wikipedia.org/wiki/Ibuprofen

    Ibuprofen was derived from propionic acid by the research arm of Boots Group during the 1960s. [73] The name is derived from the 3 functional groups: isobutyl (ibu) propionic acid (pro) phenyl (fen). [74] Its discovery was the result of research during the 1950s and 1960s to find a safer alternative to aspirin.

  3. Dexibuprofen - Wikipedia

    en.wikipedia.org/wiki/Dexibuprofen

    Ibuprofen is an α-arylpropionic acid used largely in the treatment of rheumatoid arthritis and widely used over-the counter drug for headache and minor pains. This drug has a chiral center and exists as a pair of enantiomers. (S)-Ibuprofen, the eutomer, is responsible for the desired therapeutic effect

  4. Drug nomenclature - Wikipedia

    en.wikipedia.org/wiki/Drug_nomenclature

    Drug nomenclature is the systematic naming of drugs, especially pharmaceutical drugs.In the majority of circumstances, drugs have 3 types of names: chemical names, the most important of which is the IUPAC name; generic or nonproprietary names, the most important of which are international nonproprietary names (INNs); and trade names, which are brand names. [1]

  5. Will oral phenylephrine — found in DayQuil, Theraflu and ...

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    As Yahoo Life reported last year, when taken in oral form, phenylephrine is metabolized so quickly that the amount absorbed into the bloodstream ends up being less than 1% of what was originally ...

  6. Pharmacophore - Wikipedia

    en.wikipedia.org/wiki/Pharmacophore

    As a pharmacophore model should be able to discriminate between molecules with and without bioactivity, the set of molecules should include both active and inactive compounds. Conformational analysis – Generate a set of low energy conformations that is likely to contain the bioactive conformation for each of the selected molecules.

  7. International nonproprietary name - Wikipedia

    en.wikipedia.org/wiki/International...

    An International Nonproprietary Name (INN) is an official generic and nonproprietary name given to a pharmaceutical substance or an active ingredient, [1] encompassing compounds, peptides and low-molecular-weight proteins (e.g., insulin, hormones, cytokines), as well as complex biological products, such as those used for gene therapy. [2]

  8. Flurbiprofen - Wikipedia

    en.wikipedia.org/wiki/Flurbiprofen

    Side effects are analogous to those of ibuprofen. [2] It was derived from propionic acid by the research arm of Boots UK during the 1960s, a period which also included the discovery of ibuprofen, indometacin, diclofenac, naproxen, ketoprofen, and sulindac. [3] [4]: 34 It was patented in 1964 by Boots UK and approved for medical use in 1987. [5]

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