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The endomysium contains a form of transglutaminase called "tissue transglutaminase" or "tTG" for short, and antibodies that bind to this form of transglutaminase are called endomysial autoantibodies (EmA). [6] The antiendomysial antibody test is a histological assay for patient serum binding to esophageal tissue from primate.
21817 Ensembl ENSG00000198959 ENSMUSG00000037820 UniProt P21980 P21981 RefSeq (mRNA) NM_004613 NM_198951 NM_001323316 NM_001323317 NM_001323318 NM_009373 RefSeq (protein) NP_001310245 NP_001310246 NP_001310247 NP_004604 NP_945189 NP_033399 Location (UCSC) Chr 20: 38.13 – 38.17 Mb Chr 2: 157.96 – 157.99 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Protein-glutamine gamma ...
Reference ranges (reference intervals) for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples. Reference ranges for blood tests are studied within the field of clinical chemistry (also known as "clinical biochemistry", "chemical pathology" or "pure blood chemistry"), the ...
Tissue transglutaminase: TGM2: ubiquitous: 20q11.2-q12: 190196: ... [11] may have unusually high levels of one type of transglutaminase, tissue transglutaminase. It ...
The IgG antibody is similar to AGA IgA, but is found at higher levels in patients with the IgA-less phenotype. It is also associated with coeliac disease and non-celiac gluten sensitivity. [5] [6] [7] Anti-gliadin antibodies are frequently found with anti-transglutaminase antibodies.
The class I sites were found on the carboxyl end of gliadin at positions 123–131, 144–152, and 172–180. The involvement of class I responses may be minor, since antibodies to transglutaminase correlate with pathogenesis and recognition of extracellular matrix and cell surface transglutaminase can explain the destruction within coeliac ...
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Serological CD markers (IgA tissue transglutaminase [tTGA], IgA endomysial [EmA] [6] [39] and IgG deamidated gliadin peptide [DGP] [6] [13] antibodies) are always negative in those with NCGS; [6] [12] [22] [39] in addition to specific IgA autoantibody levels, it is necessary to determine total IgA levels. [12] [30] IgG tTGA antibodies should be ...