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Most esters of these corticosteroids are not included in this list; for esters, see here instead. The most common structural modifications in synthetic corticosteroids include 1(2)- dehydrogenation , 6α-, 9α-, 16α-, and 16β- substitution (with a halogen or methyl group ), 16α,17α- acetonidation , and 17α- and 21- esterification .
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This is a list of corticosteroid esters, including esters of steroidal glucocorticoids and mineralocorticoids. [ 1 ] [ 2 ] [ 3 ] Esters of natural corticosteroids
A mineralocorticoid receptor antagonist (MRA or MCRA) [1] or aldosterone antagonist, is a diuretic drug which antagonizes the action of aldosterone at mineralocorticoid receptors. This group of drugs is often used as adjunctive therapy, in combination with other drugs, for the management of chronic heart failure .
The name mineralocorticoid derives from early observations that these hormones were involved in the retention of sodium, a mineral. The primary endogenous mineralocorticoid is aldosterone, although a number of other endogenous hormones (including progesterone [1] and deoxycorticosterone) have mineralocorticoid function.
List of – steroidal antiandrogens; List of estrogens – estrogens; List of progestogens – progestogens; List of corticosteroids – corticosteroids, including both glucocorticoids and mineralocorticoids; List of neurosteroids – excitatory, inhibitory, mixed, neurotrophic, antineurotrophic, and other neurosteroids, as well as pheromones ...
Relative to cortisol, it is said to have 10 times the glucocorticoid potency but 250 to 800 times the mineralocorticoid potency. [12] [13] Fludrocortisone acetate is a prodrug of fludrocortisone, which is the active form of the drug. [14] Plasma renin, sodium, and potassium are checked through blood tests to verify that the correct dosage is ...
Download as PDF; Printable version; In other projects ... This list may not reflect recent changes. Mineralocorticoid receptor antagonist; A.