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Pyridoxal phosphate (PLP, pyridoxal 5'-phosphate, P5P), the active form of vitamin B 6, is a coenzyme in a variety of enzymatic reactions. The International Union of Biochemistry and Molecular Biology has catalogued more than 140 PLP-dependent activities, corresponding to ~4% of all classified activities. [ 5 ]
Alfuzosin, sold under the brand name Uroxatral among others, is a medication of the α 1 blocker class. It is used to treat benign prostatic hyperplasia (BPH). [1]As an antagonist of the α 1-adrenergic receptor, it works by relaxing the muscles in the prostate and bladder neck, making urination easier.
An equianalgesic chart can be a useful tool, but the user must take care to correct for all relevant variables such as route of administration, cross tolerance, half-life and the bioavailability of a drug. [5] For example, the narcotic levorphanol is 4–8 times stronger than morphine, but also has a much longer half-life. Simply switching the ...
Heartburn, also known as pyrosis, cardialgia or acid indigestion, [2] is a burning sensation in the central chest or upper central abdomen. [ 3 ] [ 4 ] [ 5 ] Heartburn is usually due to regurgitation of gastric acid (gastric reflux) into the esophagus .
The World Health Organization recommends low-dose aspirin for the prevention of pre-eclampsia in women at high risk and recommends it be started before 20 weeks of pregnancy. [66] The United States Preventive Services Task Force recommends a low-dose regimen for women at high risk beginning in the 12th week. [ 71 ]
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Heartburn – Heartburn (Regurgitation) is a burning pain in the chest, behind the breastbone that occurs when stomach acid travel up the esophagus and causes irritation. This sometimes happens in pregnancy due to relaxation of the lower esophageal sphincter (LES), which normally keeps acidic stomach contents in the stomach. Additionally ...
This strong market position generates substantial cash flows that support shareholder returns. Turning to the specifics, the pharmaceutical giant offers investors a 4.3% dividend yield backed by a ...
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